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NG2 glia

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NG2 glia is a type of macroglia found in the central nervous system, which is distinct from astrocytes and oligodendrocytes.[1] They get their name from the expression of NG2 proteoglycan on their surface. Although their exact function is unknown, they are found engulfing nodes of Ranvier.[2] NG2 glia were believed to be the precursors of oligodendrocytes, but recent evidence suggests that they have distinct functions and divide very slowly.[3] From an evolutionary point of view, the NG2 glia attained more complexity in the mammals and primates.

References

  1. ^ Raff, MC; Miller, RH; Noble, M (1983). "A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium". Nature. 303 (5916): 390–396. doi:10.1038/303390a0. PMID 6304520.
  2. ^ PMID 10088675
  3. ^ PMID 19096367