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NG2 glia

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NG2 glia is a type of macroglia found in the central nervous system, which is distinct from astrocytes and oligodendrocytes.[1] They get their name from the expression of NG2 proteoglycan on their surface. NG2 glia are believed to be the precursors of oligodendrocytes, although recent evidence suggests that they may have other distinct functions.[2] NG2 glia are homogeneously present in the grey and white matter. In white matter, they are found along unmyelinated axons [3] as well as myelinated axons, engulfing nodes of Ranvier.[4]


Description

Function

Development

References

  1. ^ Raff, MC; Miller, RH; Noble, M (1983). "A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium". Nature. 303 (5916): 390–396. doi:10.1038/303390a0. PMID 6304520.
  2. ^ PMID 19096367
  3. ^ PMID 17293857
  4. ^ PMID 10088675