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Atroxase

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Atroxase
Identifiers
EC no.3.4.24.43
CAS no.181186-94-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins

Atroxase (EC 3.4.24.43) is an enzyme.[1] This enzyme catalyses the following chemical reaction

Cleavage of His5-Leu, Ser9-His, His10-Leu, Ala14-Leu and Tyr16-Leu of insulin B chain

This endopeptidase is present in the venom of the western diamondback rattlesnake (Crotalus atrox).

References

  1. ^ Willis, T.W. and Tu, A.T. (1988). "Purification and biochemical characterization of atroxase, a nonhemorrhagic fibrinolytic protease from western diamondback rattlesnake venom". Biochemistry. 27: 4769–4777. PMID 3167016.{{cite journal}}: CS1 maint: multiple names: authors list (link)
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