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Biotene

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Biotene (typeset as biotène) is a dental hygiene product originally manufactured by Laclede Inc. but now marketed by GlaxoSmithKline. It comes in a number of forms, including toothpaste, mouthwash and cream.

The main active ingredient in its toothpastes is sodium monofluorophosphate, and prior to the GlaxoSmithKline acquisition it also contained enzymes including glucose oxidase, lactoferrin, lactoperoxidase and lysozyme. The PBF (plaque biofilm) products also contained the enzymes mutanase and dextranase. All products have been reformulated without enzymes, most also including sodium hydroxide, as a cleaning agent [citation needed].

Patients with xerostomia (dry mouth) may use Biotène to reduce the rate of recurrence of dental plaque. However, Biotene by itself does not significantly reduce the count of Streptococcus mutans which is the primary initiator of the formation of dental plaque.[1]

See also

References

  1. ^ Lehane RJ, Murray PA, Deasy MJ (1997). "Effect of an enzymatic rinse on salivary levels of Streptococcus mutans and lactobacilli in periodontally treated patients". Periodontal Clinical Investigations. 19 (2): 17–21. PMID 9495936.{{cite journal}}: CS1 maint: multiple names: authors list (link)