Akkermansia
| Akkermansia | |
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| Genus: | Akkermansia
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| Type species | |
| A. muciniphila | |
Akkermansia is a genus in the phylum Verrucomicrobia (Bacteria).[1] The genus was first proposed in 2004 by Muriel Derrien and others, with the type species Akkermansia muciniphila (gen. nov., sp. nov).[2]
Etymology
The name Akkermansia derives from:
New Latin feminine gender noun Akkermansia, named after Antoon Akkermans, a Dutch microbiologist recognized for his contribution to microbial ecology.[3]
Species
The genus contains a single species,[3] namely A. muciniphila ( Derrien et al. 2004, (Type species of the genus).; New Latin neuter gender noun mucinum, mucin; New Latin adjective philus from Greek adjective philos (φίλος) meaning friend, loving; New Latin feminine gender adjective muciniphila, mucin-loving.)[4]
Description of Akkermansia gen. nov.
Akkermansia (Ak.ker.man'si.a. N.L. fem. n. Akkermansia derived from Antoon Akkermans, a Dutch microbiologist recognized for his contribution to microbial ecology). Cells are oval-shaped, non-motile and stain Gram-negative. Strictly anaerobic. Chemo-organotrophic. Mucolytic in pure culture.[2]: 1474
Human metabolism
Researchers have discovered that Akkermansia muciniphila may be able to be used to combat obesity and type 2 diabetes. The study was carried out with mice, overfed to contain three times more fat than its lean cousin. The obese mice were then fed the bacteria, which were shown to reduce the fat burden of the mice by half without any change to the mice's diet. The bacterium is naturally present in the human digestive tract at 3-5%, but has been seen to fall with obesity. It is thought that eating the bacterium increases the gut wall thickness, with the addition of mucin, which will block food from being absorbed by the body.[5]
See also
References
- ^ Classification of Genera AC in LPSN; Parte, Aidan C.; Sardà Carbasse, Joaquim; Meier-Kolthoff, Jan P.; Reimer, Lorenz C.; Göker, Markus (1 November 2020). "List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ". International Journal of Systematic and Evolutionary Microbiology. 70 (11): 5607–5612. doi:10.1099/ijsem.0.004332.
- ^ a b Derrien, M. (2004). "Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium". INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY. 54 (5): 1474. doi:10.1099/ijs.0.02873-0. ISSN 1466-5026.
- ^ a b Akkermansia in LPSN; Parte, Aidan C.; Sardà Carbasse, Joaquim; Meier-Kolthoff, Jan P.; Reimer, Lorenz C.; Göker, Markus (1 November 2020). "List of Prokaryotic names with Standing in Nomenclature (LPSN) moves to the DSMZ". International Journal of Systematic and Evolutionary Microbiology. 70 (11): 5607–5612. doi:10.1099/ijsem.0.004332.
- ^ Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium
- ^ Owens, Brian (13 May 2013). "Gut microbe may fight obesity and diabetes". Nature. doi:10.1038/nature.2013.12975. Retrieved 14 May 2013.
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