Svante Pääbo
Svante Pääbo | |
---|---|
Born | |
Nationality | Sweden |
Alma mater | Uppsala University |
Known for | Paleogenetics |
Awards | Gottfried Wilhelm Leibniz Prize (1992) Member of the Order of the Pour le Mérite, civil class (2008) Kistler Prize (2009) Great Cross of Merit with star (2009) Gruber Prize in Genetics (2013) |
Scientific career | |
Fields | Genetics Evolutionary Anthropology |
Institutions | Max Planck Institute for Evolutionary Anthropology |
Svante Pääbo (* 20 April 1955 in Stockholm) is a Swedish biologist specializing in evolutionary genetics.
Life
Pääbo is the son of Sune Bergström, who shared the Nobel Prize in Physiology or Medicine with Bengt I. Samuelsson and John R. Vane in 1982, and Estonian chemist Karin Pääbo.[1]
He earned his PhD from Uppsala University in 1986. Since 1997, he has been director of the Department of Genetics at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany.[2][3][4][5][6]
Work
Pääbo is known as one of the founders of paleogenetics, a discipline that uses the methods of genetics to study early humans and other ancient populations. In 1997, Pääbo and colleagues reported their successful sequencing of Neanderthal mitochondrial DNA (mtDNA), originating from a specimen found in Feldhofer grotto in the Neander valley.[7]
In August 2002, Pääbo's department published findings about the "language gene", FOXP2,[8] which is lacking or damaged in some individuals with language disabilities.
In 2006, Pääbo announced a plan to reconstruct the entire genome of Neanderthals. In 2007, he was named one of TIME Magazine's 100 most influential people of the year.[9]
In February 2009, at the Annual Meeting of the American Association for the Advancement of Science (AAAS), it was announced that the Max Planck Institute for Evolutionary Anthropology had completed the first draft version of the Neanderthal genome. Over 3 billion base pairs were sequenced in collaboration with the 454 Life Sciences Corporation. This project, led by Pääbo, will shed new light on the recent evolutionary history of modern humans.[citation needed]
In March 2010, Pääbo and his coworkers published a report about the DNA analysis of a finger bone found in the Denisova Cave in Siberia; the results suggest that the bone belonged to an extinct member of the genus Homo that had not yet been recognized, the Denisova hominin.[10]
In May 2010, Pääbo and his colleagues published a draft sequence of the Neanderthal genome in the journal Science.[11] He and his team also concluded that there was probably interbreeding between Neanderthals and Eurasian (but not African) humans.[12] There is growing support in the scientific community for this theory of admixture between archaic and anatomically-modern humans,[13] though some archaeologists remain skeptical about this conclusion.[14][needs update][better source needed]
Awards and recognitions
In 1992, he received the Gottfried Wilhelm Leibniz Prize of the Deutsche Forschungsgemeinschaft, which is the highest honour awarded in German research. Pääbo was elected a member of the Royal Swedish Academy of Sciences in 2000. In October 2009 the Foundation For the Future announced that Pääbo had been awarded the 2009 Kistler Prize for his work isolating and sequencing ancient DNA, beginning in 1984 with a 2,400-year-old mummy.[15] In June 2010 the Federation of European Biochemical Societies awarded him the Theodor Bücher Medal for outstanding achievements in Biochemistry and Molecular Biology.[16] In 2013, he received Gruber Prize in Genetics for ground breaking research in evolutionary genetics.[17]
References
- ^ Kolbert, Elizabeth, Sleeping with the Enemy, The New Yorker. 15 August 2011
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instead. - ^ "Svante Paabo at the Max Planck Institute for Evolutionary Anthropology". Retrieved 2011-07-27.
- ^ Krings, M; Stone, A; Schmitz, Rw; Krainitzki, H; Stoneking, M; Pääbo, S (July 1997). "Neandertal DNA sequences and the origin of modern humans". Cell. 90 (1): 19–30. doi:10.1016/S0092-8674(00)80310-4. ISSN 0092-8674. PMID 9230299.
{{cite journal}}
: CS1 maint: multiple names: authors list (link) - ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 12192408, please use {{cite journal}} with
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instead. - ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 20448178 , please use {{cite journal}} with
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instead.. - ^ Rincon, Paul (6 May 2010). "Neanderthal genes 'survive in us'". BBC. Retrieved 7 May 2010.
- ^ Lalueza-Fox C & Gilbert MTP (2011). Paleogenomics of Archaic Hominins. Current Biology, 21 (24): R1002-R1009.
- ^ Wade, Nicholas (7 May 2010). "Signs of Neanderthals Mating With Humans". The New York Times. Retrieved 7 May 2010.
- ^ "Foundation For the Future has selected Dr. Svante Pääbo as the 2009 winner of the Kistler Prize". Retrieved 2011-07-27.
- ^ "FEBS MEDALS: The Theodor Bücher Lecture and Medal". Retrieved 2011-07-27.
- ^ "Gruber Genetics Prize for Svante Pääbo". MAX-PLANCK-GESELLSCHAFT. Retrieved 2013-04-06.
Bibliography
- Pääbo, Svante (November 1993). "Ancient DNA". Scientific American. 269 (5): 60–66.
- "Svante Paabo publications in PubMed". Retrieved 2011-07-27.
- "Svante Paabo publications in Google Scholar". Retrieved 2011-07-27.
- "Edge: Mapping the Neanderthal Genome - A Conversation With Svante Pääbo". Retrieved 2011-07-27.
- Candee, Marjorie Dent; Block, Maxine; Rothe, Anna Herthe (2007). Current biography yearbook. New York: H. W. Wilson. ISBN 0-8242-1084-0.
{{cite book}}
: CS1 maint: multiple names: authors list (link) - Harold M. Schmeck Jr (16 April 1985). "Intact Genetic Material Extracted from an Ancient Egyptian Mummy". New York Times. (This article shows Pääbo to be the first one to extract DNA from a thousands year dead human—not Bryan Sykes who claimed to be in his books)
- Kolbert, Elizabeth. "Sleeping with the Enemy: What happened between the Neanderthals and us?". The New Yorker. No. August 15 & 22, 2011. pp. pp.64-75.
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has extra text (help)
- 1955 births
- Living people
- People from Stockholm
- Members of the United States National Academy of Sciences
- Members of the Royal Swedish Academy of Sciences
- Knight Commanders of the Order of Merit of the Federal Republic of Germany
- Population geneticists
- Swedish geneticists
- Leibniz Prize winners
- Uppsala University alumni
- Swedish people of Estonian descent
- Recipients of the Order of the Cross of Terra Mariana, 3rd Class