Jump to content

Ganesh Nagaraju

Add links
From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by 14.139.128.14 (talk) at 13:51, 21 June 2018. The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Ganesh Nagaraju
Born
India
NationalityIndian
Alma mater
Known forStudies on anti-cancer therapeutics
Awards
Scientific career
Fields
Institutions

Ganesh Nagaraju is an Indian biochemist, geneticist, cancer biologist and an associate professor at the Department of Biochemistry of the Indian Institute of Science. He was involved in the development of trans-dichloro oxovanadium (IV) complex of pyrenyl terpyridine, an anti-cancer agent. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2015.[1]

Biography

Harvard Medical School.

Ganesh Nagaraju earned his PhD from the Indian Institute of Science in 2003 and did his post-doctoral research at Harvard Medical School and Beth Israel Deaconess Medical Center.[2] On his return to India in 2007,[3] he joined his alma mater, Indian Institute of Science, where he serves as an associate professor.[4] His research focus is on cancer biology and chromosome instability and his team is involved in developing DNA repair protocols.[5] In 2016, his team developed a novel compound, trans-dichloro oxovanadium(IV) complex of pyrenyl terpyridine, a visible light inducible DNA crosslinker which could be activated by visible light and it showed properties of forming crosslinks in the DNA when cancer cells are exposed to UV-A or visible light, thus protecting the cells against the onset of cancer.[6] His studies have been documented by way of a number of articles[7][note 1] and ResearchGate, an online repository of scientific articles has listed 38 of them.[8] He has delivered invited speeches at several international conferences which included the seminar on Distinct roles of RAD51 paralogs in DNA damage responses held at Centre for DNA Fingerprinting and Diagnostics on October 4, 2016[9] and the Indo-French Conference on Recent Advances in Genome Integrity and Plasticity held at Bengaluru in December 2017.[10] He also hosts several post-doctoral and doctoral researchers at his laboratory.[11]

Awards and honors

The Department of Biotechnology (DBT) of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards in 2015.[1] Prof. K.V.Giri memorial award for best Ph.D Thesis in the year 2003. B.M.Birla Science Prize in Biology for the year 2012. Sir C.V. Raman Young Scientist award from Government of Karnataka for the year 2015.


Selected bibliography

  • Mishra, Anup; Saxena, Sneha; Kaushal, Anjali; Nagaraju, Ganesh (2018-02-01). "RAD51C/XRCC3 Facilitates Mitochondrial DNA Replication and Maintains Integrity of the Mitochondrial Genome". Molecular and Cellular Biology. 38 (3): e00489–17. doi:10.1128/MCB.00489-17.
  • Somyajit, Kumar; Banik, Bhabatosh; Saxena, Sneha; Babu, Sharath; Hande, Manoor Prakash; Chakravarty, Akhil R.; Nagaraju, Ganesh (2016-02-01). "Trans -dichlorooxovandium (IV) complex as a novel photoinducible DNA interstrand crosslinker for cancer therapy". Carcinogenesis. 37 (2): 145–156. doi:10.1093/carcin/bgv173.
  • Thakur, Roshan Singh; Basavaraju, Shivakumar; Khanduja, Jasbeer Singh; Muniyappa, K.; Nagaraju, Ganesh (2015-10-02). "Mycobacterium tuberculosis RecG Protein but Not RuvAB or RecA Protein Is Efficient at Remodeling the Stalled Replication Forks IMPLICATIONS FOR MULTIPLE MECHANISMS OF REPLICATION RESTART IN MYCOBACTERIA". Journal of Biological Chemistry. 290 (40): 24119–24139. doi:10.1074/jbc.M115.671164. PMC 4591802.{{cite journal}}: CS1 maint: unflagged free DOI (link)

See also

Notes

  1. ^ Please see Selected bibliography section

References

  1. ^ a b "Awardees of National Bioscience Awards for Career Development" (PDF). Department of Biotechnology. 2016. Retrieved 2017-11-20.
  2. ^ "DNA Repair and Disease Laboratory - Indian Institute of Science". biochem.iisc.ernet.in. 2018-05-14. Retrieved 2018-05-14.
  3. ^ "Ganesh Nagaraju, Ph.D. profile in India Cancer Research Database". www.incredb.org. 2018-05-14. Retrieved 2018-05-14.
  4. ^ "Department of Biochemistry". biochem.iisc.ernet.in. 2018-05-14. Retrieved 2018-05-14.
  5. ^ "Ganesh Nagaraju - Division of Biological Sciences, Indian Institute of Science". bio.iisc.ac.in. 2018-05-14. Retrieved 2018-05-14.
  6. ^ Taru (2018-05-14). "Breaking Cancer's back: Targeting the DNA". Indian Institute of Science. Retrieved 2018-05-14.
  7. ^ "On Google Scholar". Google Scholar. 2018-05-14. Retrieved 2018-05-14.
  8. ^ "On ResearchGate". On ResearchGate. 2018-05-14. Retrieved 2018-05-14.
  9. ^ "CDFD :: Seminar by Dr Ganesh Nagaraju". www.cdfd.org.in. 2018-05-14. Retrieved 2018-05-14.
  10. ^ "Indo-French Conference ,Indian Institute of Science (IISc), Bangalore". indo-frenchconference2017.com. 2018-05-14. Retrieved 2018-05-14.
  11. ^ "DNA Repair and Disease Laboratory - People". biochem.iisc.ernet.in. 2018-05-14. Retrieved 2018-05-14.

External links

Retrieved from "https://en.wikipedia.org/w/index.php?title=Ganesh_Nagaraju&oldid=846887299"