2,N,N-TMT: Difference between revisions
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Updating {{drugbox}} (changes to watched fields - updated 'UNII_Ref', 'ChemSpiderID_Ref', 'StdInChI_Ref', 'StdInChIKey_Ref', 'ChEMBL_Ref', 'KEGG_Ref') per Chem/Drugbox validation (report [[Wikipe |
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{{Short description|Chemical compound}} |
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{{drugbox |
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{{Drugbox |
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| verifiedrevid = |
| verifiedrevid = 428819098 |
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| IUPAC_name = (2-(2-methyl-1''H''-indol-3-yl)-1-methyl-ethyl)dimethylamine |
| IUPAC_name = (2-(2-methyl-1''H''-indol-3-yl)-1-methyl-ethyl)dimethylamine |
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| image = 2-Me-DMT.svg |
| image = 2-Me-DMT.svg |
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| width = 200px |
| width = 200px |
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<!--Clinical data--> |
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| molecular_weight = 202.30 g/mol |
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| smiles = |
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| pregnancy_AU = |
| pregnancy_AU = |
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| pregnancy_US = |
| pregnancy_US = |
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| pregnancy_category = |
| pregnancy_category = |
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| legal_AU = |
| legal_AU = |
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| legal_CA = |
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| legal_DE = NpSG |
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| legal_UK = Class A |
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<!--Pharmacokinetic data--> |
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<!--Identifiers--> |
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| ChEMBL = 7580 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = P15UO6J3FK |
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| ChemSpiderID = 9994827 |
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| PubChem = 11820174 |
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<!--Chemical data--> |
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| smiles = Cc1c(c2ccccc2[nH]1)CCN(C)C |
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| StdInChI = 1S/C13H18N2/c1-10-11(8-9-15(2)3)12-6-4-5-7-13(12)14-10/h4-7,14H,8-9H2,1-3H3 |
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| StdInChIKey = NDGCOWDSLVNLGE-UHFFFAOYSA-N |
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'''2,''N,N''- |
'''2,''N,N''-trimethyltryptamine''', '''2,''N,N''-TMT''', or '''2-Me-DMT''' is a [[tryptamine]] [[Chemical derivative|derivative]] that is a [[Psychedelic drug|psychedelic]] drug. It was invented by [[Alexander Shulgin]] and reported in his book [[TiHKAL]] (#34).<ref>[https://www.erowid.org/library/books_online/tihkal/tihkal34.shtml Erowid Online Books : "TIHKAL" - #34 2-ME-DMT<!-- Bot generated title -->]</ref> It is claimed to show psychoactive effects at a dosage of 50–100 mg orally, but these are relatively mild compared to other similar drugs, suggesting that while the 2-methyl group has blocked the binding of metabolic enzymes, it is also interfering with binding to the 5HT<sub>2A</sub> receptor target that mediates the hallucinogenic effects of these drugs. |
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== Legal status == |
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Sweden's public health agency suggested classifying 2-Me-DMT as a hazardous substance, on May 15, 2019.<ref>{{cite web | url=https://www.folkhalsomyndigheten.se/nyheter-och-press/nyhetsarkiv/2019/maj/folkhalsomyndigheten-foreslar-att-20-amnen-klassas-som-narkotika-eller-halsofarlig-vara/ | title=Folkhälsomyndigheten föreslår att 20 ämnen klassas som narkotika eller hälsofarlig vara | publisher=Folkhälsomyndigheten | language=sv | date=15 May 2019 | access-date=11 November 2019 | archive-date=20 October 2021 | archive-url=https://web.archive.org/web/20211020121058/https://www.folkhalsomyndigheten.se/nyheter-och-press/nyhetsarkiv/2019/maj/folkhalsomyndigheten-foreslar-att-20-amnen-klassas-som-narkotika-eller-halsofarlig-vara/ | url-status=dead }}</ref> |
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==See also== |
==See also== |
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== External links == |
== External links == |
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* [ |
* [https://isomerdesign.com/PiHKAL/read.php?domain=tk&id=34 2-Me-DMT entry in TiHKAL • info] |
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{{TiHKAL}} |
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{{hallucinogenic tryptamines}} |
{{hallucinogenic tryptamines}} |
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{{Tryptamines}} |
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{{DEFAULTSORT:TMT, 2,N,N-}} |
{{DEFAULTSORT:TMT, 2, N, N-}} |
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[[Category:Psychedelic tryptamines]] |
[[Category:Psychedelic tryptamines]] |
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[[Category:Dimethylamino compounds]] |
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