Miroprofen: Difference between revisions
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Updating {{drugbox}} (no changed fields - added verified revid - updated 'ChEMBL_Ref', 'ChEBI_Ref', 'KEGG_Ref', 'ChEBI_Ref') per Chem/Drugbox validation (report errors or [[user talk:CheMoB |
who mistakes "carbocyclic" for "carboxylic??? |
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{{Short description|Analgesic and NSAID}} |
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{{Unreferenced stub|auto=yes|date=December 2009}} |
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{{Drugbox |
{{Drugbox |
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| Verifiedfields = changed |
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| verifiedrevid = |
| verifiedrevid = 449584845 |
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| IUPAC_name = (''RS'')-2-(4-imidazo[1,2-''a'']pyridin-2-ylphenyl)propanoic acid |
| IUPAC_name = (''RS'')-2-(4-imidazo[1,2-''a'']pyridin-2-ylphenyl)propanoic acid |
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| image = Miroprofen.svg |
| image = Miroprofen.svg |
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| width = 250px |
| width = 250px |
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| |
| chirality = [[Racemic mixture]] |
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| drug_name = Miroprofen |
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<!--Clinical data--> |
<!--Clinical data--> |
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| tradename = |
| tradename = |
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<!--Identifiers--> |
<!--Identifiers--> |
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| CAS_number_Ref = {{cascite|correct|??}} |
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| CAS_number = 55843-86-2 |
| CAS_number = 55843-86-2 |
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| ATC_prefix = none |
| ATC_prefix = none |
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| PubChem = 68752 |
| PubChem = 68752 |
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| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
| DrugBank_Ref = {{drugbankcite|correct|drugbank}} |
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| DrugBank = |
| DrugBank = |
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| ChEBI_Ref = {{ebicite|changed|EBI}} |
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| ChEBI = 76249 |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 61997 |
| ChemSpiderID = 61997 |
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<!--Chemical data--> |
<!--Chemical data--> |
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| C=16 | H=14 | N=2 | O=2 |
| C=16 | H=14 | N=2 | O=2 |
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| molecular_weight = 266.295 g/mol |
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| smiles = O=C(O)C(c3ccc(c1nc2ccccn2c1)cc3)C |
| smiles = O=C(O)C(c3ccc(c1nc2ccccn2c1)cc3)C |
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| InChI = 1/C16H14N2O2/c1-11(16(19)20)12-5-7-13(8-6-12)14-10-18-9-3-2-4-15(18)17-14/h2-11H,1H3,(H,19,20) |
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| InChIKey = OJGQFYYLKNCIJD-UHFFFAOYAN |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI = 1S/C16H14N2O2/c1-11(16(19)20)12-5-7-13(8-6-12)14-10-18-9-3-2-4-15(18)17-14/h2-11H,1H3,(H,19,20) |
| StdInChI = 1S/C16H14N2O2/c1-11(16(19)20)12-5-7-13(8-6-12)14-10-18-9-3-2-4-15(18)17-14/h2-11H,1H3,(H,19,20) |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = OJGQFYYLKNCIJD-UHFFFAOYSA-N |
| StdInChIKey = OJGQFYYLKNCIJD-UHFFFAOYSA-N |
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| synonyms = <small>2-[4-(1,7-diazabicyclo[4.3.0]nona-2,4,6,8-tetraen-8-yl)phenyl]propanoic acid</small> |
| synonyms = Antopen; BRN 0888858; NSC 261037; Ro 07-0582; Y 9213; <small>2-[4-(1,7-diazabicyclo[4.3.0]nona-2,4,6,8-tetraen-8-yl)phenyl]propanoic acid</small> |
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}} |
}} |
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'''Miroprofen''' ([[International Nonproprietary Name|INN]]) is an [[analgesic]] and [[Non-steroidal anti-inflammatory drug|NSAID]], meaning that it has [[anti-inflammatory]], [[antipyretic]] and [[Antiplatelet drug|antiplatelet aggregation]] activity. Chemically it is a [[carboxylic acid]] belonging to the group of [[phenylpropanoic acid]]s.<ref name="Mikashima-1982">{{cite journal | vauthors = Mikashima H, Goto K | title = [Inhibitory effect of 2-(4-(2-imidazo(1,2-a)pyridyl)phenyl) propionic acid (miroprofen) on platelet aggregation and prostaglandin I2 generation (author's transl)] | journal = Yakugaku Zasshi | volume = 102 | issue = 1 | pages = 99–103 | date = January 1982 | pmid = 7045328 | doi = 10.1248/yakushi1947.102.1_99| doi-access = free }}</ref> |
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'''Miroprofen''' ([[International Nonproprietary Name|INN]]) is an [[analgesic]] and [[NSAID]]. It is a carbocyclic acid, a phenylpropionate. |
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== References == |
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Synonyms are Antopen; BRN 0888858; Miroprofen; Miroprofene; Miroprofeno; Miroprofenum; NSC 261037; Ro 07-0582; Y 9213. |
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{{reflist}} |
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{{NSAIDs}} |
{{NSAIDs}} |
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{{Prostanoidergics}} |
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[[Category: |
[[Category:Nonsteroidal anti-inflammatory drugs]] |
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[[Category:Imidazopyridines]] |
[[Category:Imidazopyridines]] |
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{{musculoskeletal-drug-stub}} |
{{musculoskeletal-drug-stub}} |
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[[bs:Miroprofen]] |