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Miroprofen: Difference between revisions

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Updating {{drugbox}} (no changed fields - added verified revid - updated 'ChEMBL_Ref', 'ChEBI_Ref', 'KEGG_Ref', 'ChEBI_Ref') per Chem/Drugbox validation (report errors or [[user talk:CheMoB
who mistakes "carbocyclic" for "carboxylic???
 
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{{Short description|Analgesic and NSAID}}
{{Unreferenced stub|auto=yes|date=December 2009}}
{{Drugbox
{{Drugbox
| Verifiedfields = changed
| verifiedrevid = 447386370
| verifiedrevid = 449584845
| IUPAC_name = (''RS'')-2-(4-imidazo[1,2-''a'']pyridin-2-ylphenyl)propanoic acid
| IUPAC_name = (''RS'')-2-(4-imidazo[1,2-''a'']pyridin-2-ylphenyl)propanoic acid
| image = Miroprofen.svg
| image = Miroprofen.svg
| width = 250px
| width = 250px
| imagename = 1 : 1 mixture (racemate)
| chirality = [[Racemic mixture]]
| drug_name = Miroprofen

<!--Clinical data-->
<!--Clinical data-->
| tradename =
| tradename =
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<!--Identifiers-->
<!--Identifiers-->
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 55843-86-2
| CAS_number = 55843-86-2
| ATC_prefix = none
| ATC_prefix = none
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| PubChem = 68752
| PubChem = 68752
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =
| DrugBank =
| ChEBI_Ref = {{ebicite|changed|EBI}}
| ChEBI = 76249
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 61997
| ChemSpiderID = 61997
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<!--Chemical data-->
<!--Chemical data-->
| C=16 | H=14 | N=2 | O=2
| C=16 | H=14 | N=2 | O=2
| molecular_weight = 266.295 g/mol
| smiles = O=C(O)C(c3ccc(c1nc2ccccn2c1)cc3)C
| smiles = O=C(O)C(c3ccc(c1nc2ccccn2c1)cc3)C
| InChI = 1/C16H14N2O2/c1-11(16(19)20)12-5-7-13(8-6-12)14-10-18-9-3-2-4-15(18)17-14/h2-11H,1H3,(H,19,20)
| InChIKey = OJGQFYYLKNCIJD-UHFFFAOYAN
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C16H14N2O2/c1-11(16(19)20)12-5-7-13(8-6-12)14-10-18-9-3-2-4-15(18)17-14/h2-11H,1H3,(H,19,20)
| StdInChI = 1S/C16H14N2O2/c1-11(16(19)20)12-5-7-13(8-6-12)14-10-18-9-3-2-4-15(18)17-14/h2-11H,1H3,(H,19,20)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = OJGQFYYLKNCIJD-UHFFFAOYSA-N
| StdInChIKey = OJGQFYYLKNCIJD-UHFFFAOYSA-N
| synonyms = <small>2-[4-(1,7-diazabicyclo[4.3.0]nona-2,4,6,8-tetraen-8-yl)phenyl]propanoic acid</small>
| synonyms = Antopen; BRN 0888858; NSC 261037; Ro 07-0582; Y 9213; <small>2-[4-(1,7-diazabicyclo[4.3.0]nona-2,4,6,8-tetraen-8-yl)phenyl]propanoic acid</small>
}}
}}


'''Miroprofen''' ([[International Nonproprietary Name|INN]]) is an [[analgesic]] and [[Non-steroidal anti-inflammatory drug|NSAID]], meaning that it has [[anti-inflammatory]], [[antipyretic]] and [[Antiplatelet drug|antiplatelet aggregation]] activity. Chemically it is a [[carboxylic acid]] belonging to the group of [[phenylpropanoic acid]]s.<ref name="Mikashima-1982">{{cite journal | vauthors = Mikashima H, Goto K | title = [Inhibitory effect of 2-(4-(2-imidazo(1,2-a)pyridyl)phenyl) propionic acid (miroprofen) on platelet aggregation and prostaglandin I2 generation (author's transl)] | journal = Yakugaku Zasshi | volume = 102 | issue = 1 | pages = 99–103 | date = January 1982 | pmid = 7045328 | doi = 10.1248/yakushi1947.102.1_99| doi-access = free }}</ref>
'''Miroprofen''' ([[International Nonproprietary Name|INN]]) is an [[analgesic]] and [[NSAID]]. It is a carbocyclic acid, a phenylpropionate.


== References ==
Synonyms are Antopen; BRN 0888858; Miroprofen; Miroprofene; Miroprofeno; Miroprofenum; NSC 261037; Ro 07-0582; Y 9213.
{{reflist}}


{{NSAIDs}}
{{NSAIDs}}
{{Prostanoidergics}}


[[Category:Non-steroidal anti-inflammatory drugs]]
[[Category:Nonsteroidal anti-inflammatory drugs]]
[[Category:Imidazopyridines]]
[[Category:Imidazopyridines]]



{{musculoskeletal-drug-stub}}
{{musculoskeletal-drug-stub}}

[[bs:Miroprofen]]