Mitoguazone: Difference between revisions

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+{{Short description|Chemical compound}}
-{{drugbox
+{{Drugbox
+| Verifiedfields = changed
+| Watchedfields = changed
+| verifiedrevid = 444738923
+| IUPAC_name = (2''E'',2<nowiki>'</nowiki>''E'')-2,2'-(1''E'',2''E'')-propane-1,2-diylidenedihydrazinecarboximidamide
+| image = mitoguazone.png
+| image2 = mitoguazone_sf.gif
+<!--Clinical data-->
+| tradename =
+| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
+| pregnancy_US = <!-- A / B            / C / D / X -->
+| pregnancy_category =
+| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
+| legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII -->
+| legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C -->
+| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
+| legal_status =
+| routes_of_administration =
+<!--Pharmacokinetic data-->
+| bioavailability =
+| protein_bound =
+| metabolism =
+| elimination_half-life =
+| excretion =
+<!--Identifiers-->
+| CAS_number_Ref = {{cascite|correct|??}}
+| CAS_number = 459-86-9
+| ATC_prefix = L01
+| ATC_suffix = XX16
+| PubChem = 5351154
+| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
+| DrugBank =
 | UNII_Ref = {{fdacite|correct|FDA}}
 | UNII = OD5Q0L447W
-| verifiedrevid = 443518984
-| IUPAC_name        = (2''E'',2<nowiki>'</nowiki>''E'')-2,2'-(1''E'',2''E'')-propane-1,2-diylidenedihydrazinecarboximidamide
-|synonyms = <small>2-<nowiki>[[</nowiki>(1''E'')-1-(Diaminomethylidenehydrazinylidene)propan-2-ylidene]amino]guanidine</small>
-| image             = mitoguazone.png
-| image2            = mitoguazone_sf.gif
-| CAS_number        = 459-86-9
-| ATC_prefix        = L01
-| ATC_suffix        = XX16
-| PubChem           = 5351154
-| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
-| DrugBank          =
 | KEGG_Ref = {{keggcite|correct|kegg}}
 | KEGG = D07258
+| ChEBI_Ref = {{ebicite|changed|EBI}}
-| C=5|H=12|N=8
+| ChEBI = 43996
-| molecular_weight  = 184.20 g/mol
+|  ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
-| bioavailability   =
+| ChemSpiderID = 4508218
-| protein_bound     =
-| metabolism        =
-| elimination_half-life =
-| excretion         =
-| pregnancy_AU      =  <!-- A / B1 / B2 / B3 / C / D / X -->
-| pregnancy_US      =  <!-- A / B            / C / D / X -->
-| pregnancy_category=
-| legal_AU =  <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
-| legal_CA =  <!-- Schedule I, II, III, IV, V, VI, VII, VIII -->
-| legal_UK =  <!-- GSL, P, POM, CD, or Class A, B, C -->
-| legal_US =  <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
-| legal_status      =
-| routes_of_administration =
-}}
+<!--Chemical data-->
-'''Mitoguazone''' (also known as methylglyoxal bis(guanylhydrazone) or MGBG) is a drug used in [[chemotherapy]].
+| C=5 | H=12 | N=8
+| synonyms = <small>2-<nowiki>[[</nowiki>(1''E'')-1-(Diaminomethylidenehydrazinylidene)propan-2-ylidene]amino]guanidine</small>
+| smiles = C\C(\C=N\NC(N)=N)=N/NC(N)=N
+| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
+| StdInChI = 1S/C5H12N8/c1-3(11-13-5(8)9)2-10-12-4(6)7/h2H,1H3,(H4,6,7,12)(H4,8,9,13)/b10-2+,11-3+
+| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
+| StdInChIKey = PKDBCJSWQUOKDO-UHFFFAOYSA-M
+}}
+'''Mitoguazone''' (also known as methylglyoxal bis(guanylhydrazone) or MGBG) is a drug used in [[chemotherapy]].<ref name="pmid2655552">{{cite journal | vauthors = Hoffmann H, Gutsche W, Amlacher R, Schulze W, Werner W, Lenk H, Wohlrab W, Haupt E | title = [Mitoguazone (methylglyoxal bis(guanylhydrazone))--its status and prospects] | language = German | journal = Archiv für Geschwulstforschung | volume = 59 | issue = 2 | pages = 135–48 | date = 1989 | pmid = 2655552 | doi = | url = }}</ref>
+== References ==
+{{Reflist}}
 {{Chemotherapeutic agents}}