Sulfamazone: Difference between revisions

Browse history interactively

← Previous edit

Content deleted Content added

VisualWikitext

@@ Line 1: / Line 1: @@
+{{Short description|Chemical compound}}
-{{drugbox
+{{more citations needed|date=April 2022}}
-| Verifiedfields = changed
+{{Drugbox
-| UNII_Ref = {{fdacite|changed|FDA}}
+| verifiedrevid = 443486461
-| UNII = D7B8U8VA9J
+| IUPAC_name = (1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-<nowiki/>{[4-[(6- methoxypyridazin-3-l)sulfamoyl]phenyl]amino} methanesulfonic acid
-| verifiedrevid = 408900204
+| image = Sulfamazone.svg
-| IUPAC_name        = (1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-{[4-[(6- methoxypyridazin-3-l)sulfamoyl]phenyl]amino} methanesulfonic acid
+| alt = Skeletal formula of sulfamazone
-| image             = Sulfamazone.svg
-| width             = 300
+| width = 300
+| image2 = Sulfamazone-3D-spacefill.png
-| CAS_number        = 65761-24-2
+| alt2 = Space-filling model of the sulfamazone molecule
-| ATC_prefix        = J01
+<!--Clinical data-->
-| ATC_suffix        = ED09
+| tradename =
-| PubChem           = 187764
+| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X -->
+| pregnancy_US = <!-- A / B            / C / D / X -->
+| pregnancy_category =
+| legal_AU = <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
+| legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII -->
+| legal_UK = <!-- GSL, P, POM, CD, or Class A, B, C -->
+| legal_US = <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
+| legal_status =
+| routes_of_administration =
+<!--Pharmacokinetic data-->
+| bioavailability =
+| protein_bound =
+| metabolism =
+| elimination_half-life =
+| excretion =
+<!--Identifiers-->
+| CAS_number = 65761-24-2
+| ATC_prefix = J01
+| ATC_suffix = ED09
+| PubChem = 187764
 | DrugBank_Ref = {{drugbankcite|correct|drugbank}}
-| DrugBank          =
+| DrugBank =
+| ChEBI = 131721
+| ChEMBL = 2104921
+| UNII_Ref = {{fdacite|correct|FDA}}
+| UNII = D7B8U8VA9J
 | KEGG_Ref = {{keggcite|correct|kegg}}
 | KEGG = D07241
+| ChemSpiderID = 163211
-| C=23 |H=24 |N=6 |O=7 |S=2
+| smiles = CC1=C(C(=O)N(N1C)C2=CC=CC=C2)C(NC3=CC=C(C=C3)S(=O)(=O)NC4=NN=C(C=C4)OC)S(=O)(=O)O
-| molecular_weight  = 560.602 g/mol
+| StdInChI = 1S/C23H24N6O7S2/c1-15-21(23(30)29(28(15)2)17-7-5-4-6-8-17)22(38(33,34)35)24-16-9-11-18(12-10-16)37(31,32)27-19-13-14-20(36-3)26-25-19/h4-14,22,24H,1-3H3,(H,25,27)(H,33,34,35)
-| bioavailability   =
+| StdInChIKey = BGLHAKAJGYLSOX-UHFFFAOYSA-N
-| protein_bound     =
+<!--Chemical data-->
-| metabolism        =
+| C=23 | H=24 | N=6 | O=7 | S=2
-| elimination_half-life =
-| excretion         =
-| pregnancy_AU      =  <!-- A / B1 / B2 / B3 / C / D / X -->
-| pregnancy_US      =  <!-- A / B            / C / D / X -->
-| pregnancy_category=
-| legal_AU =  <!-- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
-| legal_CA =  <!-- Schedule I, II, III, IV, V, VI, VII, VIII -->
-| legal_UK =  <!-- GSL, P, POM, CD, or Class A, B, C -->
-| legal_US =  <!-- OTC / Rx-only / Schedule I, II, III, IV, V -->
-| legal_status      =
-| routes_of_administration =
 }}
-'''Sulfamazone''' ([[International Nonproprietary Name|INN]]) is a [[sulfonamide (medicine)|sulfonamide]] [[antibiotic]] with [[antipyretic]] properties.
+'''Sulfamazone''' ([[International Nonproprietary Name|INN]]) is a [[sulfonamide (medicine)|sulfonamide]] [[antibiotic]] with [[antipyretic]] properties.<ref>{{cite journal | vauthors = Zhao Z, Dai X, Li C, Wang X, Tian J, Feng Y, Xie J, Ma C, Nie Z, Fan P, Qian M, He X, Wu S, Zhang Y, Zheng X | display-authors = 6 | title = Pyrazolone structural motif in medicinal chemistry: Retrospect and prospect | journal = European Journal of Medicinal Chemistry | volume = 186 | pages = 111893 | date = January 2020 | pmid = 31761383 | pmc = 7115706 | doi = 10.1016/j.ejmech.2019.111893 }}</ref>
-{{Sulfonamides and trimethoprim}}
+== References ==
-{{antibiotic-stub}}
+{{Reflist}}
+{{Sulfonamides and trimethoprim}}
 [[Category:Sulfonamide antibiotics]]
@@ Line 42: / Line 58: @@
 [[Category:Pyridazines]]
 [[Category:Sulfonic acids]]
+{{antibiotic-stub}}