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Tolpropamine: Difference between revisions

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Updating {{drugbox}} (changes to verified fields - updated 'ChEMBL_Ref') per Chem/Drugbox validation (report errors or bugs)
Add: s2cid, pages. Added the cs1 style template to denote Vancouver ("vanc") citation style, because references contain "vauthors" attribute to specify the list of authors.
 
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{{Short description|Chemical compound}}
{{drugbox
{{cs1 config|name-list-style=vanc}}
| Verifiedfields = changed
{{Drugbox
| UNII_Ref = {{fdacite|changed|FDA}}
| verifiedrevid = 437200296
| UNII = TBZ8909KFS
| IUPAC_name = ''N,N''-dimethyl-3-(4-methylphenyl)-3-phenylpropan-1-amine
| verifiedrevid = 408941788
| image = Tolpropamine.svg
| IUPAC_name = ''N,N''-dimethyl-3-(4-methylphenyl)-3-phenylpropan-1-amine

| image = Tolpropamine.svg
<!--Clinical data-->
| tradename =
| pregnancy_category =
| legal_status =
| routes_of_administration =

<!--Pharmacokinetic data-->
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =

<!--Identifiers-->
| CAS_number = 5632-44-0
| CAS_supplemental = {{CAS|3354-67-4}}
| ATC_prefix = D04
| ATC_suffix = AA12
| PubChem = 72141
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 65115
| ChemSpiderID = 65115
| UNII_Ref = {{fdacite|correct|FDA}}
| InChI = 1/C18H23N/c1-15-9-11-17(12-10-15)18(13-14-19(2)3)16-7-5-4-6-8-16/h4-12,18H,13-14H2,1-3H3
| UNII = TBZ8909KFS
| InChIKey = CINROOONPHQHPO-UHFFFAOYAS
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D07196

<!--Chemical data-->
| C=18 | H=23 | N=1
| smiles = c1cc(ccc1C(c2ccccc2)CCN(C)C)C
| smiles = c1cc(ccc1C(c2ccccc2)CCN(C)C)C
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = CINROOONPHQHPO-UHFFFAOYSA-N
| StdInChIKey = CINROOONPHQHPO-UHFFFAOYSA-N
| CAS_number = 5632-44-0
| CAS_supplemental = {{CAS|3354-67-4}} ([[hydrochloride]])
| ATC_prefix = D04
| ATC_suffix = AA12
| PubChem = 72141
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D07196
| C = 18 | H = 23 | N = 1
| molecular_weight = 253.382 g/mol
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| pregnancy_category=
| legal_status =
| routes_of_administration =
}}
}}


'''Tolpropamine''' is an [[antihistamine]] and [[anticholinergic]] used as an [[antipruritic]].
'''Tolpropamine''' is an [[antihistamine]] and [[anticholinergic]] used as an [[antipruritic]].<ref>{{cite book | vauthors = Kutscher B | chapter = Dermatologicals (D), 2. Antifungals (D01), Emollients and Protectives (D02), and Antipruritics (D04) for Dermatological Use | veditors = Ley C |title=Ullmann's Encyclopedia of Industrial Chemistry |date=2000-06-15 | pages = 1–24 |doi=10.1002/14356007.w08_w01 | isbn = 978-3-527-30385-4 | s2cid = 225510885 }}</ref>


== References ==
== References ==
{{Reflist|2}}
{{Reflist}}




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[[Category:H1 receptor antagonists]]
[[Category:H1 receptor antagonists]]
[[Category:Benzhydryl compounds]]



{{dermatologic-drug-stub}}
{{dermatologic-drug-stub}}