Comparison of international blood pressure guidelines: Difference between revisions

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Guidelines on the choice of agents and how best to step up treatment for various subgroups have changed over time and differ between countries.

A Comparison of International Guidelines on Goal BP and Initial Drug Therapy for Adults With Hypertension (adapted from JNC 8 guidelines^[1])
Guideline	Population	Goal BP, mmHg	Initial drug treatment options
AAFP 2022^[2]^[3]	General	<140/90	BP >140/90 and low-risk for CVD: Lifestyle changes BP >140/90 and CVD risk factors or failed lifestyle changes: monotherapy with thiazide-type diuretic, ACEI/ARB, and/or CCB BP >160/100: two from different classes - thiazide-type diuretic, ACEI/ARB, and/or CCB
KDIGO 2021^[4]	CKD with kidney transplant	SBP <120 <130/80	CKD: ACEI/ARB Kidney transplant: ARB or CCB
VA/DoD 2020^[5]	General Age ≥60 Age ≥60 with Diabetes	<130/90 <150/90 <140/90	Thiazide-type diuretic, ACEI/ARB, and/or CCB Black: avoid monotherapy with ACEI/ARB
NICE 2019^[6]	Age <80 Age ≥80	<140/90 <150/90	Age <55: ACEI/ARB Age ≥55 or black: CCB
ADA 2018^[7]	Diabetes Diabetes with CVD risk	<140/90 <130/80	ACEI/ARB, thiazide-like diuretic, and/or dihydropyridine CCB
ESC/ESH 2018^[8]	General age <65 General age ≥65	<130/80 <140/80	Thiazide-type diuretic, ACEI/ARB, and/or CCB CAD: add beta-blocker Resistant hypertension: add spironolactone
ACC/AHA 2017^[9]	General	<130/80	BP > 130/80: Lifestyle changes and monotherapy with thiazide-type diuretic, ACEI/ARB, and/or CCB BP >20/10 above target: Lifestyle changes and two from different classes - thiazide-type diuretic, ACEI/ARB, and/or CCB
JNC 8 2013^[1]	General age ≥60 General age <60 Diabetes CKD	<150/90 <140/90 <140/90 <140/90	Non-black: thiazide-type diuretic, ACEI/ARB, and/or CCB Black: thiazide-type diuretic, and/or CCB Diabetes: thiazide-type diuretic, ACEI/ARB, and/or CCB CKD: ACEI/ARB
CHEP 2013	General <80 y General ≥80 y Diabetes CKD	<140/90 <150/90 <130/80 <140/90	General: thiazide-type diuretic, beta-blocker (age, 60 y), ACEI (non-black) or ARB Diabetes with additional risk : ACEI/ARB Diabetes without additional risk : ACEI/ARB, thiazide, or DHPCCB CKD: ACEI, or ARB
ISHIB	Black, lower risk Target organ damage or CVD risk	<135/85 <130/80	Diuretic or CCB

Abbreviations:

AAFP – American Academy of Family Physicians
ACC – American College of Cardiology
ACEI – angiotensin-converting enzyme inhibitor
ADA – American Diabetes Association
AHA – American Heart Association
ARB – angiotensin receptor blocker
CCB – calcium channel blocker
CHEP – Canadian Hypertension Education Program
CKD – chronic kidney disease
CVD – cardiovascular disease
DHPCCB – dihydropyridine calcium channel blocker
ESC – European Society of Cardiology
ESH – European Society of Hypertension
ISHIB – International Society for Hypertension in Blacks
JNC – Joint National Committee
KDIGO – Kidney Disease: Improving Global Outcome
NICE – National Institute for Health and Clinical Excellence (United Kingdom)

References

^ ^a ^b James, PA.; Oparil, S.; Carter, BL.; Cushman, WC.; Dennison-Himmelfarb, C.; Handler, J.; Lackland, DT.; Lefevre, ML.; Mackenzie, TD.; Ogedegbe, Olugbenga; Smith, Sidney C.; Svetkey, Laura P.; Taler, Sandra J.; Townsend, Raymond R.; Wright, Jackson T.; Narva, Andrew S.; Ortiz, Eduardo (Dec 2013). "2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults: Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC 8)". JAMA. 311 (5): 507–20. doi:10.1001/jama.2013.284427. PMID 24352797.
^ Coles, Sarah; Fisher, Lynn; Lin, Kenneth W.; Lyon, Corey; Vosooney, Alexis A.; Bird, Melanie D. (December 2022). "Blood Pressure Targets in Adults With Hypertension: A Clinical Practice Guideline From the AAFP". American Family Physician. 106 (6): Online. ISSN 1532-0650. PMID 36521481.
^ Clarke, S. Lindsey (October 2023). "Hypertension in Adults: Initial Evaluation and Management". American Family Physician. 108 (4): 352–359. ISSN 1532-0650. PMID 37843942.
^ Cheung, Alfred K.; Chang, Tara I.; Cushman, William C.; Furth, Susan L.; Hou, Fan Fan; Ix, Joachim H.; Knoll, Gregory A.; Muntner, Paul; Pecoits-Filho, Roberto; Sarnak, Mark J.; Tobe, Sheldon W.; Tomson, Charles R.V.; Mann, Johannes F.E. (March 2021). "KDIGO 2021 Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease". Kidney International. 99 (3): S1–S87. doi:10.1016/j.kint.2020.11.003.
^ U.S. Department of Veterans Affairs. "VA/DoD clinical practice guideline for the diagnosis and management of hypertension in the primary care setting". VA/DoD Clinical Practice Guidelines. Retrieved 2024-03-25.
^ "Overview | Hypertension in adults: diagnosis and management | Guidance | NICE". www.nice.org.uk. 2019-08-28. Retrieved 2024-03-24.
^ Passarella, Pasquale; Kiseleva, Tatiana A.; Valeeva, Farida V.; Gosmanov, Aidar R. (2018-08-01). "Hypertension Management in Diabetes: 2018 Update". Diabetes Spectrum. 31 (3): 218–224. doi:10.2337/ds17-0085. ISSN 1040-9165. PMC 6092891. PMID 30140137.
^ Williams, Bryan; Mancia, Giuseppe; Spiering, Wilko; Agabiti Rosei, Enrico; Azizi, Michel; et al. (1 September 2018). "2018 ESC/ESH Guidelines for the management of arterial hypertension". European Heart Journal. 39 (33): 3021–3104. doi:10.1093/eurheartj/ehy339.
^ Whelton, Paul K.; Carey, Robert M.; Aronow, Wilbert S.; Casey, Donald E.; Collins, Karen J.; Dennison Himmelfarb, Cheryl; DePalma, Sondra M.; Gidding, Samuel; Jamerson, Kenneth A.; Jones, Daniel W.; MacLaughlin, Eric J.; Muntner, Paul; Ovbiagele, Bruce; Smith, Sidney C.; Spencer, Crystal C. (2018-05-15). "2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults". Journal of the American College of Cardiology. 71 (19): e127–e248. doi:10.1016/j.jacc.2017.11.006.

[jnc8-1] James, PA.; Oparil, S.; Carter, BL.; Cushman, WC.; Dennison-Himmelfarb, C.; Handler, J.; Lackland, DT.; Lefevre, ML.; Mackenzie, TD.; Ogedegbe, Olugbenga; Smith, Sidney C.; Svetkey, Laura P.; Taler, Sandra J.; Townsend, Raymond R.; Wright, Jackson T.; Narva, Andrew S.; Ortiz, Eduardo (Dec 2013). "2014 Evidence-Based Guideline for the Management of High Blood Pressure in Adults: Report From the Panel Members Appointed to the Eighth Joint National Committee (JNC 8)". JAMA. 311 (5): 507–20. doi:10.1001/jama.2013.284427. PMID 24352797.

[2] Coles, Sarah; Fisher, Lynn; Lin, Kenneth W.; Lyon, Corey; Vosooney, Alexis A.; Bird, Melanie D. (December 2022). "Blood Pressure Targets in Adults With Hypertension: A Clinical Practice Guideline From the AAFP". American Family Physician. 106 (6): Online. ISSN 1532-0650. PMID 36521481.

[3] Clarke, S. Lindsey (October 2023). "Hypertension in Adults: Initial Evaluation and Management". American Family Physician. 108 (4): 352–359. ISSN 1532-0650. PMID 37843942.

[4] Cheung, Alfred K.; Chang, Tara I.; Cushman, William C.; Furth, Susan L.; Hou, Fan Fan; Ix, Joachim H.; Knoll, Gregory A.; Muntner, Paul; Pecoits-Filho, Roberto; Sarnak, Mark J.; Tobe, Sheldon W.; Tomson, Charles R.V.; Mann, Johannes F.E. (March 2021). "KDIGO 2021 Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease". Kidney International. 99 (3): S1–S87. doi:10.1016/j.kint.2020.11.003.

[5] U.S. Department of Veterans Affairs. "VA/DoD clinical practice guideline for the diagnosis and management of hypertension in the primary care setting". VA/DoD Clinical Practice Guidelines. Retrieved 2024-03-25.

[6] "Overview | Hypertension in adults: diagnosis and management | Guidance | NICE". www.nice.org.uk. 2019-08-28. Retrieved 2024-03-24.

[7] Passarella, Pasquale; Kiseleva, Tatiana A.; Valeeva, Farida V.; Gosmanov, Aidar R. (2018-08-01). "Hypertension Management in Diabetes: 2018 Update". Diabetes Spectrum. 31 (3): 218–224. doi:10.2337/ds17-0085. ISSN 1040-9165. PMC 6092891. PMID 30140137.

[8] Williams, Bryan; Mancia, Giuseppe; Spiering, Wilko; Agabiti Rosei, Enrico; Azizi, Michel; et al. (1 September 2018). "2018 ESC/ESH Guidelines for the management of arterial hypertension". European Heart Journal. 39 (33): 3021–3104. doi:10.1093/eurheartj/ehy339.

[9] Whelton, Paul K.; Carey, Robert M.; Aronow, Wilbert S.; Casey, Donald E.; Collins, Karen J.; Dennison Himmelfarb, Cheryl; DePalma, Sondra M.; Gidding, Samuel; Jamerson, Kenneth A.; Jones, Daniel W.; MacLaughlin, Eric J.; Muntner, Paul; Ovbiagele, Bruce; Smith, Sidney C.; Spencer, Crystal C. (2018-05-15). "2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults". Journal of the American College of Cardiology. 71 (19): e127–e248. doi:10.1016/j.jacc.2017.11.006.

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@@ Line 15: / Line 15: @@
 |BP >140/90 and low-risk for CVD: Lifestyle changes
-BP >140/90 and CVD risk factors or failed lifestyle changes: monotherapy with thiazide-type diuretic, ACEI/ARB, or CCB
+BP >140/90 and CVD risk factors or failed lifestyle changes: monotherapy with thiazide-type diuretic, ACEI/ARB, and/or CCB
-BP >160/100: two from different classes - thiazide-type diuretic, ACEI/ARB, or CCB
+BP >160/100: two from different classes - thiazide-type diuretic, ACEI/ARB, and/or CCB
 |-
 | {{Tooltip|KDIGO|Kidney Disease: Improving Global Outcome}} 2021<ref>{{Cite journal |last=Cheung |first=Alfred K. |last2=Chang |first2=Tara I. |last3=Cushman |first3=William C. |last4=Furth |first4=Susan L. |last5=Hou |first5=Fan Fan |last6=Ix |first6=Joachim H. |last7=Knoll |first7=Gregory A. |last8=Muntner |first8=Paul |last9=Pecoits-Filho |first9=Roberto |last10=Sarnak |first10=Mark J. |last11=Tobe |first11=Sheldon W. |last12=Tomson |first12=Charles R.V. |last13=Mann |first13=Johannes F.E. |date=March 2021 |title=KDIGO 2021 Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease |journal=Kidney International |language=en |volume=99 |issue=3 |pages=S1–S87 |doi=10.1016/j.kint.2020.11.003}}</ref>
@@ Line 36: / Line 36: @@
 <140/90
-|Thiazide-type diuretic, ACEI/ARB, or CCB
+|Thiazide-type diuretic, ACEI/ARB, and/or CCB
 Black: avoid monotherapy with ACEI/ARB
 |-
@@ Line 53: / Line 53: @@
 | <140/90
 <130/80
-| ACEI/ARB, thiazide-like diuretic, or dihydropyridine CCB
+| ACEI/ARB, thiazide-like diuretic, and/or dihydropyridine CCB
+|-
+| {{Tooltip|ESC|European Society of Cardiology}}/{{Tooltip|ESH|European Society of Hypertension}} 2018<ref>{{cite journal |last1=Williams |first1=Bryan |last2=Mancia |first2=Giuseppe |last3=Spiering |first3=Wilko |last4=Agabiti Rosei |first4=Enrico |last5=Azizi |first5=Michel |last6=Burnier |first6=Michel |last7=Clement |first7=Denis L |last8=Coca |first8=Antonio |last9=de Simone |first9=Giovanni |last10=Dominiczak |first10=Anna |last11=Kahan |first11=Thomas |last12=Mahfoud |first12=Felix |last13=Redon |first13=Josep |last14=Ruilope |first14=Luis |last15=Zanchetti |first15=Alberto |last16=Kerins |first16=Mary |last17=Kjeldsen |first17=Sverre E |last18=Kreutz |first18=Reinhold |last19=Laurent |first19=Stephane |last20=Lip |first20=Gregory Y H |last21=McManus |first21=Richard |last22=Narkiewicz |first22=Krzysztof |last23=Ruschitzka |first23=Frank |last24=Schmieder |first24=Roland E |last25=Shlyakhto |first25=Evgeny |last26=Tsioufis |first26=Costas |last27=Aboyans |first27=Victor 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|last201=Chazova |first201=Irina |last202=Lovic |first202=Dragan |last203=Filipova |first203=Slavomira |last204=Brguljan |first204=Jana |last205=Segura |first205=Julian |last206=Gottsäter |first206=Anders |last207=Pechère-Bertschi |first207=Antoinette |last208=Erdine |first208=Serap |last209=Sirenko |first209=Yuriy |last210=Brady |first210=Adrian |display-authors=5 |title=2018 ESC/ESH Guidelines for the management of arterial hypertension |journal=European Heart Journal |date=1 September 2018 |volume=39 |issue=33 |pages=3021–3104 |doi=10.1093/eurheartj/ehy339}}</ref>
+| General age <65
+General age ≥65
+| <130/80
+<140/80
+| Thiazide-type diuretic, ACEI/ARB, and/or CCB
+CAD: add beta-blocker
+Resistant hypertension: add spironolactone
 |-
 | {{Tooltip|ACC|American College of Cardiology}}/{{Tooltip|AHA|American Heart Association}} 2017<ref>{{Cite journal |last=Whelton |first=Paul K. |last2=Carey |first2=Robert M. |last3=Aronow |first3=Wilbert S. |last4=Casey |first4=Donald E. |last5=Collins |first5=Karen J. |last6=Dennison Himmelfarb |first6=Cheryl |last7=DePalma |first7=Sondra M. |last8=Gidding |first8=Samuel |last9=Jamerson |first9=Kenneth A. |last10=Jones |first10=Daniel W. |last11=MacLaughlin |first11=Eric J. |last12=Muntner |first12=Paul |last13=Ovbiagele |first13=Bruce |last14=Smith |first14=Sidney C. |last15=Spencer |first15=Crystal C. |date=2018-05-15 |title=2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults |journal=Journal of the American College of Cardiology |language=en |volume=71 |issue=19 |pages=e127–e248 |doi=10.1016/j.jacc.2017.11.006}}</ref>
 |General
 |<130/80
-|BP > 130/80: Lifestyle changes and monotherapy with thiazide-type diuretic, ACEI/ARB, or CCB
+|BP > 130/80: Lifestyle changes and monotherapy with thiazide-type diuretic, ACEI/ARB, and/or CCB
-BP >20/10 above target: Lifestyle changes and two from different classes - thiazide-type diuretic, ACEI/ARB, or CCB
+BP >20/10 above target: Lifestyle changes and two from different classes - thiazide-type diuretic, ACEI/ARB, and/or CCB
 |-
 | {{Tooltip|JNC 8|Joint National Committee}} 2013<ref name="jnc8" />
@@ Line 75: / Line 86: @@
 <140/90
-| Non-black: [[Thiazide-like diuretic|thiazide-type diuretic]], [[ACEI]]/[[Angiotensin II receptor blocker|ARB]], or [[Calcium channel blocker|CCB]]
+| Non-black: [[Thiazide-like diuretic|thiazide-type diuretic]], [[ACEI]]/[[Angiotensin II receptor blocker|ARB]], and/or [[Calcium channel blocker|CCB]]
-Black: thiazide-type diuretic, or CCB
+Black: thiazide-type diuretic, and/or CCB
-Diabetes: thiazide-type diuretic, ACEI/ARB, or CCB
-CKD: ACEI/ARB
-|-
-| {{Tooltip|ESC|European Society of Cardiology}}/{{Tooltip|ESH|European Society of Hypertension}} 2018<ref>{{cite journal |last1=Williams |first1=Bryan |last2=Mancia |first2=Giuseppe |last3=Spiering |first3=Wilko |last4=Agabiti Rosei |first4=Enrico |last5=Azizi |first5=Michel |last6=Burnier |first6=Michel |last7=Clement |first7=Denis L |last8=Coca |first8=Antonio |last9=de Simone |first9=Giovanni |last10=Dominiczak |first10=Anna |last11=Kahan |first11=Thomas |last12=Mahfoud |first12=Felix |last13=Redon |first13=Josep |last14=Ruilope |first14=Luis |last15=Zanchetti |first15=Alberto |last16=Kerins |first16=Mary |last17=Kjeldsen |first17=Sverre E |last18=Kreutz |first18=Reinhold |last19=Laurent |first19=Stephane |last20=Lip |first20=Gregory Y H |last21=McManus |first21=Richard |last22=Narkiewicz |first22=Krzysztof |last23=Ruschitzka |first23=Frank |last24=Schmieder |first24=Roland E |last25=Shlyakhto |first25=Evgeny |last26=Tsioufis |first26=Costas |last27=Aboyans |first27=Victor |last28=Desormais |first28=Ileana |last29=De Backer |first29=Guy |last30=Heagerty |first30=Anthony M |last31=Agewall |first31=Stefan |last32=Bochud |first32=Murielle |last33=Borghi |first33=Claudio |last34=Boutouyrie |first34=Pierre |last35=Brguljan |first35=Jana |last36=Bueno |first36=Héctor |last37=Caiani |first37=Enrico G |last38=Carlberg |first38=Bo |last39=Chapman |first39=Neil |last40=Cífková |first40=Renata |last41=Cleland |first41=John G F |last42=Collet |first42=Jean-Philippe |last43=Coman |first43=Ioan Mircea |last44=de Leeuw |first44=Peter W |last45=Delgado |first45=Victoria |last46=Dendale |first46=Paul |last47=Diener |first47=Hans-Christoph |last48=Dorobantu |first48=Maria |last49=Fagard |first49=Robert |last50=Farsang |first50=Csaba |last51=Ferrini |first51=Marc |last52=Graham |first52=Ian M |last53=Grassi |first53=Guido |last54=Haller |first54=Hermann |last55=Hobbs |first55=F D Richard |last56=Jelakovic |first56=Bojan |last57=Jennings |first57=Catriona |last58=Katus |first58=Hugo A |last59=Kroon |first59=Abraham A |last60=Leclercq |first60=Christophe |last61=Lovic |first61=Dragan |last62=Lurbe |first62=Empar |last63=Manolis |first63=Athanasios J |last64=McDonagh |first64=Theresa A |last65=Messerli |first65=Franz |last66=Muiesan |first66=Maria Lorenza |last67=Nixdorff |first67=Uwe |last68=Olsen |first68=Michael Hecht |last69=Parati |first69=Gianfranco |last70=Perk |first70=Joep |last71=Piepoli |first71=Massimo Francesco |last72=Polonia |first72=Jorge |last73=Ponikowski |first73=Piotr |last74=Richter |first74=Dimitrios J |last75=Rimoldi |first75=Stefano F |last76=Roffi |first76=Marco |last77=Sattar |first77=Naveed |last78=Seferovic |first78=Petar M |last79=Simpson |first79=Iain A |last80=Sousa-Uva |first80=Miguel |last81=Stanton |first81=Alice V |last82=van de Borne |first82=Philippe |last83=Vardas |first83=Panos |last84=Volpe |first84=Massimo |last85=Wassmann |first85=Sven |last86=Windecker |first86=Stephan |last87=Zamorano |first87=Jose Luis |last88=Windecker |first88=Stephan |last89=Aboyans |first89=Victor |last90=Agewall |first90=Stefan |last91=Barbato |first91=Emanuele |last92=Bueno |first92=Héctor |last93=Coca |first93=Antonio |last94=Collet |first94=Jean-Philippe |last95=Coman |first95=Ioan Mircea |last96=Dean |first96=Veronica |last97=Delgado |first97=Victoria |last98=Fitzsimons |first98=Donna |last99=Gaemperli |first99=Oliver |last100=Hindricks |first100=Gerhard |last101=Iung |first101=Bernard |last102=Jüni |first102=Peter |last103=Katus |first103=Hugo A |last104=Knuuti |first104=Juhani |last105=Lancellotti |first105=Patrizio |last106=Leclercq |first106=Christophe |last107=McDonagh |first107=Theresa A |last108=Piepoli |first108=Massimo Francesco |last109=Ponikowski |first109=Piotr |last110=Richter |first110=Dimitrios J |last111=Roffi |first111=Marco |last112=Shlyakhto |first112=Evgeny |last113=Simpson |first113=Iain A |last114=Sousa-Uva |first114=Miguel |last115=Zamorano |first115=Jose Luis |last116=Tsioufis |first116=Costas |last117=Lurbe |first117=Empar |last118=Kreutz |first118=Reinhold |last119=Bochud |first119=Murielle |last120=Rosei |first120=Enrico Agabiti |last121=Jelakovic |first121=Bojan |last122=Azizi |first122=Michel |last123=Januszewics |first123=Andrzej |last124=Kahan |first124=Thomas |last125=Polonia |first125=Jorge |last126=van de Borne |first126=Philippe |last127=Williams |first127=Bryan |last128=Borghi |first128=Claudio |last129=Mancia |first129=Giuseppe |last130=Parati |first130=Gianfranco |last131=Clement |first131=Denis L |last132=Coca |first132=Antonio |last133=Manolis |first133=Athanasios |last134=Lovic |first134=Dragan |last135=Benkhedda |first135=Salim |last136=Zelveian |first136=Parounak |last137=Siostrzonek |first137=Peter |last138=Najafov |first138=Ruslan |last139=Pavlova |first139=Olga |last140=De Pauw |first140=Michel |last141=Dizdarevic-Hudic |first141=Larisa |last142=Raev |first142=Dimitar |last143=Karpettas |first143=Nikos |last144=Linhart |first144=Aleš |last145=Olsen |first145=Michael Hecht |last146=Shaker |first146=Amin Fouad |last147=Viigimaa |first147=Margus |last148=Metsärinne |first148=Kaj |last149=Vavlukis |first149=Marija |last150=Halimi |first150=Jean-Michel |last151=Pagava |first151=Zurab |last152=Schunkert |first152=Heribert |last153=Thomopoulos |first153=Costas |last154=Páll |first154=Dénes |last155=Andersen |first155=Karl |last156=Shechter |first156=Michael |last157=Mercuro |first157=Giuseppe |last158=Bajraktari |first158=Gani |last159=Romanova |first159=Tatiana |last160=Trušinskis |first160=Kārlis |last161=Saade |first161=Georges A |last162=Sakalyte |first162=Gintare |last163=Noppe |first163=Stéphanie |last164=DeMarco |first164=Daniela Cassar |last165=Caraus |first165=Alexandru |last166=Wittekoek |first166=Janneke |last167=Aksnes |first167=Tonje Amb |last168=Jankowski |first168=Piotr |last169=Polonia |first169=Jorge |last170=Vinereanu |first170=Dragos |last171=Baranova |first171=Elena I |last172=Foscoli |first172=Marina |last173=Dikic |first173=Ana Djordjevic |last174=Filipova |first174=Slavomira |last175=Fras |first175=Zlatko |last176=Bertomeu-Martínez |first176=Vicente |last177=Carlberg |first177=Bo |last178=Burkard |first178=Thilo |last179=Sdiri |first179=Wissem |last180=Aydogdu |first180=Sinan |last181=Sirenko |first181=Yuriy |last182=Brady |first182=Adrian |last183=Weber |first183=Thomas |last184=Lazareva |first184=Irina |last185=Backer |first185=Tine De |last186=Sokolovic |first186=Sekib |last187=Jelakovic |first187=Bojan |last188=Widimsky |first188=Jiri |last189=Viigimaa |first189=Margus |last190=Pörsti |first190=Ilkka |last191=Denolle |first191=Thierry |last192=Krämer |first192=Bernhard K |last193=Stergiou |first193=George S |last194=Parati |first194=Gianfranco |last195=Trušinskis |first195=Kārlis |last196=Miglinas |first196=Marius |last197=Gerdts |first197=Eva |last198=Tykarski |first198=Andrzej |last199=de Carvalho Rodrigues |first199=Manuel |last200=Dorobantu |first200=Maria |last201=Chazova |first201=Irina |last202=Lovic |first202=Dragan |last203=Filipova |first203=Slavomira |last204=Brguljan |first204=Jana |last205=Segura |first205=Julian |last206=Gottsäter |first206=Anders |last207=Pechère-Bertschi |first207=Antoinette |last208=Erdine |first208=Serap |last209=Sirenko |first209=Yuriy |last210=Brady |first210=Adrian |display-authors=5 |title=2018 ESC/ESH Guidelines for the management of arterial hypertension |journal=European Heart Journal |date=1 September 2018 |volume=39 |issue=33 |pages=3021–3104 |doi=10.1093/eurheartj/ehy339}}</ref>
-| General nonelderly
-General elderly
-General ≥80&nbsp;y
-Diabetes
-CKD
-CKD + [[proteinuria]]
-| <140/90
-<150/90
-<150/90
-<140/85
-<140/90
-<130/90
-| General: [[beta-blocker]], [[diuretic]], CCB, ACEI/ARB
-Diabetes: ACEI/ARB
+Diabetes: thiazide-type diuretic, ACEI/ARB, and/or CCB
 CKD: ACEI/ARB