Genetically modified bird: Difference between revisions
m Dating maintenance tags: {{According to whom?}} |
→Uses: fix ref |
||
| (One intermediate revision by the same user not shown) | |||
| Line 2: | Line 2: | ||
==Uses== |
==Uses== |
||
One use of genetically modified birds is to reduce the spread of avian disease. Workers at [[Roslin Institute]] have genetically modified a strain of chicken that does not transmit [[avian flu]] to other birds. The genetic modification is a small molecule designed to prevent the flu virus reproducing after it has infected a chicken. This [[RNA]] molecule prevents the virus reproduction by mimicing the region of the flu virus genome that controls replication. It is referred to as a "decoy" because it diverts the flu virus enzyme, the [[polymerase]], from functions that are required for virus replication.<ref name="Roslin">{{cite web|url=http://www.roslin.ed.ac.uk/public-interest/gm-chickens/|title=GM chickens that don't transmit bird flu|publisher=The University of Edinburgh|accessdate=September 3, 2015}}</ref> |
|||
==References== |
==References== |
||
Revision as of 15:38, 3 September 2015
Genetically modified birds are an important[according to whom?] category of genetically modified organisms. Attempts to produce transgenic birds began before 1980.[1]
Uses
One use of genetically modified birds is to reduce the spread of avian disease. Workers at Roslin Institute have genetically modified a strain of chicken that does not transmit avian flu to other birds. The genetic modification is a small molecule designed to prevent the flu virus reproducing after it has infected a chicken. This RNA molecule prevents the virus reproduction by mimicing the region of the flu virus genome that controls replication. It is referred to as a "decoy" because it diverts the flu virus enzyme, the polymerase, from functions that are required for virus replication.[2]
References
- ^ Scott, B.B. and Lois, C. (2005). "Generation of tissue-specific transgenic birds with lentiviral vectors". Proc. Natl. Acad. Sci. U.S.A. 102 (45): 16443–16447. doi:10.1073/pnas.0508437102.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ^ "GM chickens that don't transmit bird flu". The University of Edinburgh. Retrieved September 3, 2015.