Janeway lesion: Difference between revisions
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==Supporting images == |
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*[http://medirec.ncvc.go.jp/cgi-bin/get_file?FILE_NAME=S2004081858020001.jpg figure1]{{Dead link|date=November 2014}} |
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*[http://aapredbook.aappublications.org/content/images/small/2006/1/126_06.gif figure2] |
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{{Eponymous medical signs for circulatory and respiratory systems}} |
{{Eponymous medical signs for circulatory and respiratory systems}} |
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Revision as of 17:57, 14 September 2015
| Janeway lesion | |
|---|---|
| Specialty | Infectious diseases  |
Janeway lesions are non-tender, small erythematous or haemorrhagic macular or nodular lesions on the palms or soles only a few millimeters in diameter that are indicative of infective endocarditis.[1] Pathologically, the lesion is described to be a microabscess of the dermis with marked necrosis and inflammatory infiltrate not involving the epidermis.[1] They are caused by septic emboli which deposit bacteria, forming microabscesses.[2] Janeway lesions are distal, flat, ecchymotic, and painless.
Osler's nodes and Janeway lesions are similar, but Osler's nodes present with tenderness and are of immunologic origin.[3]
Eponym
They are named after Edward Janeway (1841-1911), a prominent American physician and pathologist who initially described the lesions.
See also
References
- ^ a b Farrior, J.B.; Silverman M.E. (1976). "A consideration of the differences between a Janeway's lesion and an Osler's node in infectious endocarditis". Chest. 70 (2): 239–243. doi:10.1378/chest.70.2.239. PMID 947688.
- ^ Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 7th ed., Churchill Livingstone 2009.
- ^ Farrior JB, Silverman ME (August 1976). "A consideration of the differences between a Janeway's lesion and an Osler's node in infectious endocarditis". Chest. 70 (2): 239–243. doi:10.1378/chest.70.2.239. PMID 947688.
Template:Eponymous medical signs for circulatory and respiratory systems