Mir-46/mir-47/mir-281 microRNA precursor family

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Mir-46/mir-47/mir-281 microRNA precursor family
Identifiers
Other data
PDB structuresPDBe

In molecular biology, mir-46 (MI0000017) and mir-47 (MI0000018) are microRNA expressed in C. elegans from related hairpin precursor sequences.[1] The predicted hairpin precursor sequences for Drosophila mir-281 (MI0000366, MI0000370)[2][3] are also related and, hence, belong to this family. The hairpin precursors (represented here) are predicted based on base pairing and cross-species conservation; their extents are not known. In this case, the mature sequences are expressed from the 3' arms of the hairpin precursors.

References

  1. ^ Lau, NC (2001). "An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans". Science. 294 (5543): 858–862. doi:10.1126/science.1065062. PMID 11679671. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)
  2. ^ Lai, EC (2003). "Computational identification of Drosophila microRNA genes". Genome Biol. 4 (7): R42–. doi:10.1186/gb-2003-4-7-r42. PMC 193629. PMID 12844358. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)CS1 maint: extra punctuation (link) CS1 maint: unflagged free DOI (link)
  3. ^ Aravin, AA (2003). "The small RNA profile during Drosophila melanogaster development". Dev Cell. 5 (2): 337–350. doi:10.1016/S1534-5807(03)00228-4. PMID 12919683. {{cite journal}}: Unknown parameter |coauthors= ignored (|author= suggested) (help)

External links