Etybenzatropine: Difference between revisions

Browse history interactively

← Previous edit

Content deleted Content added

VisualWikitext

@@ Line 1: / Line 1: @@
+{{Short description|Chemical compound}}
+{{cs1 config|name-list-style=vanc}}
 {{Drugbox
+| Watchedfields = changed
-| verifiedrevid = 443996506
+| verifiedrevid = 447824918
-| IUPAC_name = (1''R'',5''R'')-3-(dicyclohexylmethoxy)-8-ethyl-<br>8-azabicyclo[3.2.1]octane
+| IUPAC_name = (3-''endo'')-3-(Diphenylmethoxy)-8-ethyl-8-azabicyclo[3.2.1]octane
 | image = Etybenzatropine.svg
@@ Line 9: / Line 12: @@
 <!--Identifiers-->
+| CAS_number_Ref = {{cascite|correct|??}}
 | CAS_number = 524-83-4
 | ATC_prefix = N04
@@ Line 22: / Line 26: @@
 <!--Chemical data-->
 | C=22 | H=27 | N=1 | O=1
+| smiles = CCN1[C@@H]2CC[C@H]1C[C@H](C2)OC(c3ccccc3)c4ccccc4
-| molecular_weight = 321.456 g/mol
-| smiles = CCN4[C@@H]1CC[C@H]4C[C@H](C1)OC(c2ccccc2)c3ccccc3
-| InChI = 1/C22H27NO/c1-2-23-19-13-14-20(23)16-21(15-19)24-22(17-9-5-3-6-10-17)18-11-7-4-8-12-18/h3-12,19-22H,2,13-16H2,1H3/t19-,20+,21+
-| InChIKey = PHTMLLGDZBZXMW-AERCQKQUBH
 | StdInChI_Ref = {{stdinchicite|correct|chemspider}}
 | StdInChI = 1S/C22H27NO/c1-2-23-19-13-14-20(23)16-21(15-19)24-22(17-9-5-3-6-10-17)18-11-7-4-8-12-18/h3-12,19-22H,2,13-16H2,1H3/t19-,20+,21+
@@ Line 32: / Line 33: @@
 }}
-'''Etybenzatropine''' ([[International Nonproprietary Name|INN]]), also known as '''ethybenztropine''' ([[United States Adopted Name|USAN]], [[British Approved Name|BAN]]) and '''tropethydrylin''', is an [[anticholinergic]]/[[antihistamine]] marketed under the [[trade name]]s '''Panolid''', '''Ponalid''', and '''Ponalide''', which is used as an [[antiparkinsonian agent]]. Like its [[analogue_(chemistry)|analogue]] [[benzatropine]], it may act as a [[dopamine reuptake inhibitor]].{{Citation needed|date=June 2011}}
+'''Etybenzatropine''' ([[International Nonproprietary Name|INN]]), also known as '''ethybenztropine''' ([[United States Adopted Name|USAN]], [[British Approved Name|BAN]]) and '''tropethydrylin''', is an [[anticholinergic]]/[[antihistamine]] marketed under the [[trade name]]s '''Panolid''', '''Ponalid''', and '''Ponalide''', which is used as an [[Management of Parkinson's disease#Medication|antiparkinsonian agent]].<ref name="pmid2779590">{{cite journal | vauthors = Pourcher E, Bonnet AM, Kefalos J, Dubois B, Agid Y | title = Effects of etybenzatropine and diazepam on levodopa-induced diphasic dyskinesias in Parkinson's disease | journal = Movement Disorders | volume = 4 | issue = 3 | pages = 195–201 | date = 1989 | pmid = 2779590 | doi = 10.1002/mds.870040301 | s2cid = 1826853 }}</ref> Like its [[analogue (chemistry)|analogue]] [[benzatropine]], it may act as a [[dopamine reuptake inhibitor]].{{Citation needed|date=June 2011}}
 == See also ==
@@ Line 39: / Line 40: @@
 == References ==
 {{Reflist|2}}
 {{Antiparkinson}}
+{{Navboxes
-{{Cholinergics}}
+| title = [[Pharmacodynamics]]
-{{Dopaminergics}}
+| titlestyle = background:#ccccff
-{{Histaminergics}}
+| list1 =
+{{Histamine receptor modulators}}
+{{Monoamine reuptake inhibitors}}
+{{Muscarinic acetylcholine receptor modulators}}
+}}
 [[Category:Antiparkinsonian agents]]
 [[Category:Muscarinic antagonists]]
 [[Category:Tropanes]]
-[[Category:Ethers]]
+[[Category:Diphenylmethanol ethers]]
 {{nervous-system-drug-stub}}
-[[fr:Étybenzatropine]]