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Telaprevir (category NS3/4A protease inhibitors)inhibitors. Specifically, telaprevir inhibits the hepatitis C viral enzyme NS3/4A serine protease. Telaprevir is only indicated for use against hepatitis...12 KB (1,128 words) - 06:18, 17 September 2023
protein found in the hepatitis C virus. It acts as a cofactor for the enzyme NS3. Beld M, Penning M, van Putten M, et al. (October 1998). "Hepatitis C virus...753 bytes (76 words) - 04:20, 16 July 2023
Voxilaprevir (category NS3/4A protease inhibitors)Voxilaprevir is a hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease inhibitor (by Gilead) that is used in combination with sofosbuvir and...4 KB (119 words) - 16:37, 28 January 2023- Hepatitis C virus nonstructural protein 3 (redirect from NS3 (HCV))Nonstructural protein 3 (NS3), also known as p-70, is a viral nonstructural protein that is 70 kDa cleavage product of the hepatitis C virus polyprotein...2 KB (250 words) - 04:26, 16 July 2023
Ciluprevir (category NS3/4A protease inhibitors)first-in-class NS3/4A protease inhibitor to enter clinical development and tested in human. Ciluprevir is a potent competitive reversible inhibitor of NS3/4A protease...4 KB (221 words) - 23:58, 3 April 2023- Sofosbuvir/velpatasvir/voxilaprevir (category NS3/4A protease inhibitors)Sofosbuvir NS5B RNA polymerase inhibitor Velpatasvir NS5A inhibitor Voxilaprevir NS3/4A protease inhibitor Clinical data Trade names Vosevi AHFS/Drugs.com Monograph...6 KB (161 words) - 03:41, 14 April 2024
Asunaprevir (category NS3/4A protease inhibitors)Asunaprevir is an inhibitor of the hepatitis C virus enzyme serine protease NS3. Asunaprevir is being tested in combination with pegylated interferon and...7 KB (271 words) - 05:20, 7 April 2024
Danoprevir (category NS3/4A protease inhibitors)an orally available 15-membered macrocyclic peptidomimetic inhibitor of NS3/4A HCV protease. It contains acylsulfonamide, fluoroisoindole and tert-butyl...7 KB (487 words) - 04:54, 20 October 2023
Vaniprevir (category NS3/4A protease inhibitors)Vaniprevir (MK-7009) is a macrocyclic hepatitis C virus (HCV) NS3/4A protease inhibitor, developed by Merck & Co., which is currently in clinical testing...3 KB (145 words) - 20:58, 1 December 2023
Sovaprevir (category NS3/4A protease inhibitors)virus. It is under development by Achillion Pharmaceuticals. It acts as a NS3/4A inhibitor. Sovaprevir received fast track status from the U.S. Food and...3 KB (91 words) - 23:50, 11 November 2023
Glecaprevir/pibrentasvir (category NS3/4A protease inhibitors)moderate to severe liver disease. Glecaprevir works by blocking the protein NS3/4A protease, while pibrentasvir works by blocking NS5A. The combination was...10 KB (870 words) - 03:38, 14 April 2024
viral RNAs ability to replicate, NS3 has little impact on the assembly of the virus. Only in the NS3/NS4A complex can the NS3 protease reach peak activity...32 KB (3,927 words) - 19:21, 19 April 2024
Bukit Gombak MRT station (redirect from NS3 station)NS3 Bukit Gombak 武吉甘柏 புக்கிட் கோம்பாக் Mass Rapid Transit (MRT) station Platform B of Bukit Gombak MRT station General information Location 802 Bukit...5 KB (259 words) - 20:59, 17 December 2023
Narlaprevir (category NS3/4A protease inhibitors)Narlaprevir (trade name Arlansa, codenamed SCH 900518), is an inhibitor of NS3/4A serine protease, intended for the treatment of chronic hepatitis C caused...13 KB (1,100 words) - 23:50, 9 February 2024
Paritaprevir (category NS3/4A protease inhibitors)Paritaprevir (previously known as ABT-450) is an acylsulfonamide inhibitor of the NS3-4A serine protease manufactured by Abbott Laboratories that shows promising...6 KB (352 words) - 19:28, 20 December 2023- Pestivirus NS3 polyprotein peptidase (EC 3.4.21.113, border disease virus NS3 endopeptidase, BDV NS3 endopeptidase, bovine viral diarrhea virus NS3 endopeptidase...3 KB (279 words) - 15:20, 26 August 2023
Grazoprevir (category NS3/4A protease inhibitors)is a second generation hepatitis C virus protease inhibitor acting at the NS3/4A protease targets. It has good activity against a range of HCV genotype...9 KB (636 words) - 08:37, 2 June 2023
Faldaprevir (category NS3/4A protease inhibitors)Faldaprevir was an experimental drug for the treatment of hepatitis C (HCV). It was being developed by Boehringer-Ingelheim and reached Phase III clinical...4 KB (192 words) - 20:12, 3 January 2024- Elbasvir/grazoprevir (category NS3/4A protease inhibitors)elbasvir (an inhibitor of hepatitis C virus's NS5A protein) and grazoprevir (an NS3/4A inhibitor). It is used to treat chronic hepatitis C virus (HCV) genotypes...20 KB (1,817 words) - 05:19, 7 April 2024
- nonstructural protein 3 (NS3). The NS2-3 autoprotease acts by making a single cleavage between the junction of NS2 and NS3. While the NS2 protein itself...9 KB (1,152 words) - 00:49, 3 December 2023
- HCV NS3/4A Protease Activity”, in PLOS ONE[1], →DOI: No apparent hepatopathological alterations were observed in liver tissue sections from the NS3/4A
- (15): 1444–1457. DOI:10.1056/NEJMra1808246. The Zika virus protease NS2B-NS3 catalyses the processing of the viral precursor polyprotein as an essential
- Name Interchange NS1 / EW24 Jurong East East West Line NS2 Bukit Batok NS3 Bukit Gombak NS4 / BP1 Choa Chu Kang NS5 Yew Tee NS7 Kranji NS8 Marsiling