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  • Thumbnail for Erythromycin
    Erythromycin is an antibiotic used for the treatment of a number of bacterial infections. This includes respiratory tract infections, skin infections,...
    41 KB (3,748 words) - 08:27, 27 April 2024
  • Thumbnail for Saccharopolyspora erythraea
    macrolide antibiotic erythromycin. Cytochrome P450 eryF (CYP107A1) originally from the bacterium is responsible for the biosynthesis of the antibiotic by...
    3 KB (297 words) - 11:54, 13 May 2024
  • {\displaystyle \rightleftharpoons } dTDP + erythromycin D The enzyme is involved in erythromycin biosynthesis. Yuan Y, Chung HS, Leimkuhler C, Walsh CT...
    2 KB (221 words) - 13:47, 26 August 2023
  • erythronolide B (EB) which is the first step of biosynthesis of the macrolide antibiotic erythromycin. This bacterial enzyme belongs to CYP family CYP107...
    2 KB (204 words) - 04:44, 14 May 2024
  • Thumbnail for Cholesterol
    cholesterol for growth. Cholesterol also serves as a precursor for the biosynthesis of steroid hormones, bile acid and vitamin D. Elevated levels of cholesterol...
    79 KB (8,518 words) - 01:29, 20 May 2024
  • Thumbnail for Ergotamine
    also contraindicated if patient is taking macrolide antibiotics (e.g., erythromycin), certain HIV protease inhibitors (e.g., ritonavir, nelfinavir, indinavir)...
    22 KB (1,316 words) - 06:48, 20 May 2024
  • Thumbnail for Macrolide
    tacrolimus. The first macrolide discovered was erythromycin, which was first used in 1952. Erythromycin was widely used as a substitute to penicillin in...
    25 KB (2,804 words) - 13:58, 4 April 2024
  • Thumbnail for Colchicine
    taken with other drugs that inhibit P-glycoprotein and CYP3A4, such as erythromycin or clarithromycin. People taking macrolide antibiotics, ketoconazole...
    53 KB (5,618 words) - 16:09, 17 May 2024
  • Thumbnail for Clindamycin
    14-membered ring macrolides, such as erythromycin. During a D-test, bacteria of the iMLSB phenotype demonstrate in vitro erythromycin-induced in vitro resistance...
    44 KB (4,052 words) - 22:15, 15 May 2024
  • PMC 26699. PMID 10051557. Staunton J (June 1998). "Combinatorial biosynthesis of erythromycin and complex polyketides". Current Opinion in Chemical Biology...
    23 KB (2,963 words) - 21:58, 1 September 2023
  • biosynthesis, and application of polyketides has evolved. It is a large and diverse group of secondary metabolites caused by its complex biosynthesis...
    21 KB (2,213 words) - 10:06, 7 March 2024
  • Thumbnail for Desosamine
    high level of microbial resistance) such as the commonly prescribed erythromycin, azithromycin, clarithroymcin, methymycin, narbomycin, oleandomycin,...
    7 KB (670 words) - 18:56, 30 April 2023
  • Thumbnail for Carbomycin
    similar to that of erythromycin. In testing the response of 74 strains of bacteria, their susceptibility across carbomycin and erythromycin was consistent...
    10 KB (836 words) - 00:17, 2 May 2023
  • Thumbnail for Lipid
    Lipid (section Biosynthesis)
    anticancer agents are polyketides or polyketide derivatives, such as erythromycins, tetracyclines, avermectins, and antitumor epothilones. Eukaryotic cells...
    70 KB (7,365 words) - 18:19, 18 May 2024
  • Thumbnail for Oleandomycin
    synthesized from strains of Streptomyces antibioticus. It is weaker than erythromycin. It used to be sold under the brand name Sigmamycine, combined with tetracycline...
    11 KB (990 words) - 08:32, 19 May 2024
  • Thumbnail for Nicotine
    while the pyrrolidine is derived from N-methyl-Δ1-pyrrollidium cation. Biosynthesis of the two component structures proceeds via two independent syntheses...
    134 KB (13,937 words) - 14:10, 21 May 2024
  • Thumbnail for Saxitoxin
    Saxitoxin biosynthesis is the first non-terpene alkaloid pathway described for bacteria, though the exact mechanism of saxitoxin biosynthesis is still...
    28 KB (2,772 words) - 21:24, 22 January 2024
  • Thumbnail for Androstenedione
    an endogenous weak androgen steroid hormone and intermediate in the biosynthesis of estrone and of testosterone from dehydroepiandrosterone (DHEA). It...
    19 KB (1,899 words) - 15:35, 24 January 2024
  • Thumbnail for 17α-Hydroxyprogesterone
    hormone related to progesterone. It is also a chemical intermediate in the biosynthesis of many other endogenous steroids, including androgens, estrogens, glucocorticoids...
    13 KB (1,059 words) - 09:02, 24 January 2024
  • Thumbnail for Pikromycin
    1002/cber.19510840306. Y. Xue & D. Sherman (2001). "Biosynthesis and Combinatorial Biosynthesis of Pikromycin-Related Macrolides in Streptomyces venezuelae"...
    7 KB (555 words) - 00:03, 8 December 2023
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