22 caliber, or 5.6mm caliber, refers to a common firearms bore diameter of 0.22 in (5.6 mm). Both .22 Long Rifle and 5.56×45mm NATO are very widely used, and it is also a popular air gun pellet caliber.
.22 in caliber rimfire variations include:
- .22 Long Rifle (LR), the most common cartridge type of this caliber, often referred to simply as ".22 caliber"
- .22 BB (Bulleted Breech Cap)
- .22 CB (Conical Ball Cap)
- .22 CB cap, an American rimfire cartridge
- .22 Long, same length, but lighter bullet than .22 LR
- .22 Extra Long, an American rimfire rifle and handgun cartridge
- .22 Short, used mostly in pocket pistols and mini-revolvers
- .22 Winchester Rimfire, an American rimfire rifle cartridge
- .22 WMR, (.22 Winchester Magnum Rimfire) a cartridge that is longer and more powerful than a .22 LR
- .22 Winchester Automatic, an American rimfire rifle cartridge
.22 inch centerfire cartridges include:
- 5.56×45mm NATO, an intermediate cartridge widely used in AR-15 style rifles
- .22 Accelerator, a special loading of the .30-30, .308, and .30-06 cartridges that is manufactured by Remington
- .22 Eargesplitten Loudenboomer, a cartridge for a rifle
- .22 Hornet, a powerful variation, also known as 5.6×35R mm 5.728mm
- .22 Remington Jet, an American centerfire revolver and rifle cartridge
- .22 BR Remington, a wildcat cartridge commonly used in varmint hunting and benchrest shooting
- .22 Savage Hi-Power, a.k.a. 5.6×52R, .22 Savage Hi-power, .22 Imp, a cartridge similar to the 22 Hornet introduced by Savage in 1912
- .22 Spitfire, an American rifle cartridge
- .22 PPC, a firearm cartridge used primarily in benchrest shooting
- .22 TCM (a.k.a. .22 Micro-Mag), a 9mm diameter case necked to a .22 caliber bullet and designed to load into standard 9mm magazines
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