3,5-Dimethylpiperidine
Appearance
(Redirected from 3,5-Lupetidine)
Names | |
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Preferred IUPAC name
3,5-Dimethylpiperidine | |
Other names
3,5-Lupetidine
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
ECHA InfoCard | 100.047.922 |
EC Number |
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PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C7H15N | |
Molar mass | 113.204 g·mol−1 |
Appearance | Colorless liquid |
Density | 0.853 g/mL (mixture) |
Boiling point | 144 °C (291 °F; 417 K) |
Low | |
Solubility in other solvents | Most organic solvents |
Refractive index (nD)
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1.4454 |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards
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Flammable |
GHS labelling: | |
Warning | |
H226, H315, H319, H335 | |
P210, P233, P240, P241, P242, P243, P261, P264, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P370+P378, P403+P233, P403+P235, P405, P501 | |
Flash point | 33 °C (91 °F; 306 K) |
Related compounds | |
Related compounds
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2,6-Dimethylpiperidine Piperidine |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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3,5-Dimethylpiperidines are chemical compounds with the formula C5H8(CH3)2NH. Two diastereomers exist: the achiral R,S isomer and the chiral R,R/S,S enantiomeric pair. 3,5-Dimethylpiperidine is a precursor to tibric acid.
The compound is typically prepared by hydrogenation of 3,5-dimethylpyridine. Both diastereomers also arise from the reduction of 3,5-dimethylpyridine with lithium triethylborohydride.[1]
References
[edit]- ^ Blough, Bruce E.; Carroll; F. Ivy (1993). "Reduction of isoquinoline and pyridine-containing heterocycles with lithium triethylborohydride (Super-Hydride)". Tetrahedron Letters. 34 (45): 7239–42. doi:10.1016/S0040-4039(00)79297-5.