XRN1 (gene)
| 5'-3' exoribonuclease 1 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | XRN1 | ||||||
| NCBI gene | 54464 | ||||||
| HGNC | 30654 | ||||||
| OMIM | 607994 | ||||||
| RefSeq | NM_019001 | ||||||
| UniProt | Q8IZH2 | ||||||
| Other data | |||||||
| Locus | Chr. 3 q23 | ||||||
| |||||||
5'-3' exoribonuclease 1 (XRN1) is an exoribonuclease enzyme encoded in humans by the XRN1 gene. This enzyme is hydrolyses RNA in the 5’ to 3’ direction.[1]
References
- ^ Mullen, T. E.; Marzluff, W. F. (1 January 2008). "Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'". Genes & Development. 22 (1): 50–65. doi:10.1101/gad.1622708.
External links
- XRN1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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