Pachymic acid
Appearance
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Names | |
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IUPAC name
3β-(Acetyloxy)-16α-hydroxy-24-methylidenelanost-8-en-21-oic acid
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Systematic IUPAC name
(2R)-2-[(1R,2R,3aR,5aR,6S,9aS,11aR)-7-(Acetyloxy)-2-hydroxy-3a,6,6,9a,11a-pentamethyl-2,3,3a,4,5,5a,6,7,8,9,9a,10,11,11a-tetradecahydro-1H-cyclopenta[a]phenanthren-1-yl]-6-methyl-5-methylideneheptanoic acid | |
Identifiers | |
3D model (JSmol)
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ChEMBL | |
ChemSpider | |
KEGG | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C33H52O5 | |
Molar mass | 528.76 g/mol |
Density | 1.1±0.1 g/cm3 |
Boiling point | 612.2±55.0 °C at 760 mmHg |
Hazards | |
Flash point | 184.7±25.0 °C [citation needed] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Pachymic acid is a naturally occurring steroid that can be extracted from the parasitic fungus Wolfiporia extensa (synonym Wolfiporia cocos). The dried sclerotia of the fungus is used as a traditional Chinese medicine, and pachymic acid is thought to be the principal bioactive component of it.[1]
Effects
Pachymic acid is known to inhibit the Epstein–Barr virus and to inhibit the snake venom phospholipase A2.[2] It also has antitumor and anti-inflammatory properties.[1]
References
- ^ a b Shu, Shaohua; Chen, Bei; Zhou, Mengchun; Zhao, Xinmei; Xia, Haiyang; Wang, Mo (2013). "De Novo Sequencing and Transcriptome Analysis of Wolfiporia cocos to Reveal Genes Related to Biosynthesis of Triterpenoids". PLOS ONE. 8 (8): e71350. Bibcode:2013PLoSO...871350S. doi:10.1371/journal.pone.0071350. PMC 3743799. PMID 23967197.
- ^ "Pachymic acid Biological Test Results". PubChem compound database. 3 March 2016.