Rolziracetam

Rolziracetam
Clinical data
Other names	2,6,7,8-tetrahydro-1H-pyrrolizine-3,5-dione
Routes of; administration	Oral
ATC code	none;
Legal status
Legal status	AU: S4 (Prescription only); US: Unscheduled;
Identifiers
	IUPAC name dihydro-1H-pyrrolizine-3,5(2H,6H)-dione;
CAS Number	18356-28-0 ;
PubChem CID	71893;
ChemSpider	64906 ;
UNII	RES9I0LGG5;
ChEMBL	ChEMBL51396 ;
CompTox Dashboard (EPA)	DTXSID80171444 ;
Chemical and physical data
Formula	C7H9N2O2
Molar mass	153.161 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C2N1C(=O)CCC1CC2;
	InChI InChI=1S/C7H9NO2/c9-6-3-1-5-2-4-7(10)8(5)6/h5H,1-4H2 ; Key:IEZDOKQWPWZVQF-UHFFFAOYSA-N ;
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Rolziracetam is a nootropic drug of the racetam family.

Rolziracetam was found to improve performance on a delayed-response task in aged rhesus monkeys. It has a wide margin of safety in animals and has been evaluated for use in cognitively impaired human subjects.^[1]

References

^ Butler DE, Leonard JD, Caprathe BW, L'Italien YJ, Pavia MR, Hershenson FM, Poschel PH, Marriott JG (March 1987). "Amnesia-reversal activity of a series of cyclic imides". Journal of Medicinal Chemistry. 30 (3): 498–503. doi:10.1021/jm00386a010. PMID 3820221.

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[pmid3820221-1] Butler DE, Leonard JD, Caprathe BW, L'Italien YJ, Pavia MR, Hershenson FM, Poschel PH, Marriott JG (March 1987). "Amnesia-reversal activity of a series of cyclic imides". Journal of Medicinal Chemistry. 30 (3): 498–503. doi:10.1021/jm00386a010. PMID 3820221.

[1]

v t e Racetams
Racetams	Nootropics: Aniracetam Coluracetam Dimiracetam Doliracetam Dupracetam Fasoracetam Imuracetam Nebracetam Nefiracetam Nicoracetam Oxiracetam Piperacetam Piracetam Pramiracetam Rolipram Rolziracetam Anticonvulsants: Brivaracetam Etiracetam Levetiracetam Seletracetam
Phenylpiracetams	Nootropics and/or stimulants: Cebaracetam Methylphenylpiracetam E1R ((4R,5S)-methylphenylpiracetam) Phenylpiracetam (phenotropil; fonturacetam) MRZ-9547 ((R)-phenylpiracetam) (S)-Phenylpiracetam RGPU-95 (chlorophenylpiracetam) Anticonvulsants: Phenylpiracetam hydrazide
Racetam-like	Nootropics: Aloracetam Molracetam Omberacetam (Noopept) Tenilsetam Traneurocin (cycloprolylglycine; NA-831) Anticonvulsants: Padsevonil

See also

References