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Elissa S. Epel

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Elissa S. Epel
Born
Carmel-by-the-Sea, California, US
Parent(s)David Epel
Lois Epel
Academic background
EducationPitzer College
BA, psychology and psychobiology, Stanford University
PhD, Psychology, 1999, Yale University
ThesisCan stress shape your body?: stress and cortisol reactivity among women with central body fat distribution (1999)
Academic advisorsPeter Salovey, Jeannette Ickovics, Kelly D. Brownell
Academic work
InstitutionsUniversity of California, San Francisco

Elissa Sarah Epel is an American health psychologist. She is a professor in the Department of Psychiatry at the University of California, San Francisco (UCSF), director of UCSF’s Aging, Metabolism, and Emotion Center, and associate director of the Center for Health and Community.

Early life and education

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Epel was born in Carmel-by-the-Sea, California to biologist David Epel and psychologist Lois Epel.[1] Growing up, she would follow her father to Woods Hole, Massachusetts during the summer and study in marine laboratories.[1][2] Upon graduating from Carmel High School in 1986, she attended Pitzer College and worked as a resident assistant.[3] She spent two years there before transferring to Stanford University for her Bachelor of Arts degree in Zoology. Following Stanford, Epel intended on becoming a doctor and worked as a research assistant at the University of California, San Francisco (UCSF). While there, she realized she wished to pursue a career in health psychology and enrolling in graduate school.[4]

Epel completed her PhD in clinical and health psychology at Yale University and her clinical internship at the VA Palo Alto Health Care System.[5] She wrote her dissertation under the guidance of Peter Salovey, Jeannette Ickovics, and Kelly Brownell.[6] Epel then returned to UCSF for her postdoctoral fellowship in psychology and medicine under the advisory of Nancy Adler.[4]

Career

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Upon completing her formal education, Epel was appointed an assistant professor in the Department of Psychiatry at UCSF in 2002.[4] In this role, she led a research team in studying 39 women between the ages of 20 to 50 who experienced stress as caregivers of chronically ill children. They examined the telomeres and telomerase in women. Their results indicated that doctors could monitor telomere length and telomerase levels for signs of adverse effects.[7][8] In 2007, Epel led another study showing a correlation between weight gain and stress.[9]

During her tenure, Epel founded the UCSF Center for Obesity Assessment, Study, and Treatment and directed the Aging, Metabolism, and Emotions Lab. She was also the Associate Director of the UCSF Center for Health and Community and UCSF Nutrition Obesity Research Center. As a result of her research on stress pathways, Epel was elected a member of the National Academy of Medicine in 2016.[10] The following year, she was recognized as an "Influencer in Aging" by the Alliance for Aging Research for her "for her groundbreaking work on the psychological, social, and behavioral processes related to chronic psychological stress which accelerate biological aging."[11]

Epel co-published her first book with Elizabeth Blackburn in 2017, titled ''The Telomere Effect: A Revolutionary Approach to Living Younger, Healthier, Longer.[2] While studying telomeres and the replenishing enzyme, telomerase, they discovered a vital role played by these protective caps that revolved around one central idea: aging of cells. Since telomeres shorten with every division of a cell, replenishing these caps is essential to long-term cell growth. Through research and data, they explained that people that lead stressful lives exhibit less telomerase functioning in the body, which leads to a decrease in the dividing capabilities of the cell. Once telomeres shorten drastically, the cells can no longer divide, meaning the tissues they replenish with every division would therefore die out, highlighting the aging mechanism in humans.[12] To increase telomerase activity in people with stress-filled lives, they suggested moderate exercise, even 15 minutes a day, which has been proven to stimulate telomerase activity and replenish the telomere.[13]

During the COVID-19 pandemic, Epel created a free webinar series focused on facilitating reentry to ease people's anxieties about the New normal.[14][15] She also published The geroscience agenda: Toxic stress, hormetic stress, and the rate of aging through the Ageing Research Reviews.[16] Her research team was also named the winner of the inaugural round of Healthy Longevity Catalyst Awards, a multiyear, multimillion-dollar international competition seeking breakthrough innovations to extend human health and function later in life. Their project was focused on testing the potency of hormetic stress to reduce depression and slow biological aging.[17] In 2021, Epel was recognized by Clarivate as being among as one of the top 1% of researchers globally.[18] Epel also released her second book, "The Stress Prescription: 7 days to more joy and ease," which was named a 2023 Independent Book Store bestseller in health and fitness.[19]

Selected publications

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  • The Telomere Effect: the New Science of Living Younger (2017)
  • The Stress Prescription: Seven Days to More Joy and Ease (The Seven Days Series) (2022)

References

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  1. ^ a b "Carmel High graduate named to National Academy of Medicine". The Monterey County Herald. October 19, 2016. Retrieved May 28, 2021.
  2. ^ a b Ride, Sally (August 23, 2017). "Researchers team up to share key insights on telomeres and health". sallyridescience.ucsd.edu. Retrieved May 29, 2021.
  3. ^ Murphy, Johanna (1987). "R.A's, Mentors Speak Out On Their Expectations" (PDF). pitzer.edu. p. 5. Retrieved May 29, 2021.
  4. ^ a b c "Elissa Sarah Epel Award for Distinguished Scientific Early Career Contributions to Psychology" (PDF). foodaddictionsummit.org. American Psychologist. November 2008. Retrieved May 28, 2021.
  5. ^ "Elissa Epel, PhD". amecenter.ucsf.edu. Retrieved May 28, 2021.
  6. ^ "Alumna and Nobel Prize Winner Write Guide to Healthy Aging". gsas.yale.edu. January 23, 2017. Retrieved May 29, 2021.
  7. ^ Epel, Elissa S.; Blackburn, Elizabeth H.; Lin, Jue; Dhabhar, Firdaus S.; Adler, Nancy E.; Morrow, Jason D.; Cawthon, Richard M. (December 7, 2004). "Accelerated telomere shortening in response to life stress". Proceedings of the National Academy of Sciences of the United States of America. 101 (49): 17312–17315. doi:10.1073/pnas.0407162101. PMC 534658. PMID 15574496.
  8. ^ "Aging link: A landmark observation". Colorado Springs Gazette. November 30, 2004. Retrieved May 29, 2021 – via newspaperarchive.com.
  9. ^ Howard, Schripps (February 25, 2007). "Got a big belly? It might be caused by stress?". Annapolis Sunday Capital. Retrieved May 29, 2021 – via newspaperarchive.com.
  10. ^ "Epel elected to the National Academy of Medicine". psych.ucsf.edu. October 17, 2016. Retrieved May 29, 2021.
  11. ^ Roznovsky, Nicholas (April 21, 2017). "Epel selected as "Influencer in Aging," will be honored by Alliance for Aging Research in September". psychiatry.ucsf.edu. Retrieved May 29, 2021.
  12. ^ "The Telomere Effect". amecenter.ucsf.edu.
  13. ^ Barton, Adriana (January 13, 2017). "A Nobel Prize winner's guide to living longer". The Globe and Mail. Archived from the original on January 13, 2017. Retrieved May 28, 2021.
  14. ^ Reynolds, Brandon R. (April 10, 2020). "From apps to expert advice, invaluable resources for well-being during the coronavirus pandemic". psychiatry.ucsf.edu. Retrieved May 29, 2021.
  15. ^ "Emotional Well-Being Webinars". psychiatry.ucsf.edu. 2021. Archived from the original on May 29, 2021. Retrieved May 29, 2021.
  16. ^ Epel, Elissa S. (November 2020). "The geroscience agenda: Toxic stress, hormetic stress, and the rate of aging". Ageing Research Reviews. 63: 101167. doi:10.1016/j.arr.2020.101167. PMC 7520385. PMID 32979553.
  17. ^ "Project led by trio of DPBS researchers receives Healthy Longevity Catalyst Award". psychiatry.ucsf.edu. October 15, 2020. Retrieved May 29, 2021.
  18. ^ "More than 30 Researchers Among Most Influential". University of California, San Francisco. November 30, 2022. Retrieved March 6, 2023.
  19. ^ "The Indie Healthy Living Bestseller List". American Booksellers Association. January 18, 2023. Retrieved March 6, 2023.
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