Ephraim Levin
 | The topic of this article may not meet Wikipedia's general notability guideline. (July 2023) |
 | This article's tone or style may not reflect the encyclopedic tone used on Wikipedia. (February 2020) |
Ephraim Y. Levin, (February 22, 1933, Baltimore, Maryland, - November 20, 2020).[1][2] 1957 BA and MA, 1953, MD, 1957, all at Johns Hopkins University. Internship and residencies at Johns Hopkins Hospital and Sinai Hospital of Baltimore. Married Ruth Lee Shefferman June 17, 1956; Four children: Joshua, Rebecca, Daniel, and Michael. Served in USPHS 1953-1998, on active duty 1958-1960 and 1974-1998. With Seymour Kaufman discovered the role of ascorbic acid in the enzymatic hydroxylation of dopamine to form norepinephrine, the first evidence for a specific metabolic function for this vitamin[3] Fellowship with Konrad Bloch at Harvard University 1961-1963, under auspices of Sinai Hospital. On Faculty of Pediatrics at Johns Hopkins School of Medicine 1963-1974.[4] Along with Vagn Flyger, demonstrated the partial deficiency of uroporphyrinogen cosynthetase in congenital erythropoietic porphyria of cattle and human beings, its occurrence in asymptomatic carriers of the disease, in fibroblasts as well as in bone marrow, and its probable cause of red bones in fox squirrels.[5][6] He once beat Solomon Golumb in a chess game.
References
- ^ "Ephraim Levin". Washington Jewish Week. 2020-12-02. Retrieved 2021-01-20.
- ^ "Ephraim Levin". Sagel Bloomfield Danzansky Goldberg Funeral Care Inc. Retrieved 12 August 2021.
- ^ LEVIN, EY; LEVENBERG, B; KAUFMAN, S (July 1960). "The enzymatic conversion of 3,4-dihydroxyphenylethylamine to norepinephrine". The Journal of Biological Chemistry. 235 (7): 2080–6. doi:10.1016/S0021-9258(18)69366-4. PMID 14416204.
- ^ Johns Hopkins University, Programs in Human Genetics https://profiles.nlm.nih.gov/JQ/B/B/J/C/_/jqbbjc.pdf
- ^ Levin, Ephraim Y.; Flyger, Vagn (October 1971). "Uroporphyrinogen III Cosynthetase Activity in the Fox Squirrel ( Sciurus niger )". Science. 174 (4004): 59–60. doi:10.1126/science.174.4004.59. PMID 5120867. S2CID 26381717.
- ^ Romeo, Giovanni; Levin, Ephraim Y. (July 1969). "Uroporphyrinogen III Cosynthetase in Human Congenital Erythropoietic Porphyria". Proceedings of the National Academy of Sciences. 63 (3): 856–863. doi:10.1073/pnas.63.3.856. PMC 223531. PMID 5259767.