Isopropyl mercaptan

Isopropyl mercaptan
Names
	Other names 2-Propanethiol; Propane-2-thiol; 2-propanthiol; 2-propane thiol; Isopropyl mercaptan; Isopropanethiol; Isopropylthiol; 2-Mercaptopropane; 2-Propylmercaptan; 1-Methylethanethiol;
Identifiers
CAS Number	75-33-2;
3D model (JSmol)	Interactive image;
Beilstein Reference	605260
ChEBI	CHEBI:8474;
ChEMBL	ChEMBL1897156;
ChemSpider	6124;
ECHA InfoCard	100.000.784
EC Number	200-861-4;
KEGG	C08391;
PubChem CID	6364;
UNII	E52LR62ETC;
UN number	2402
CompTox Dashboard (EPA)	DTXSID1025481 ;
	InChI InChI=1S/C3H8S/c1-3(2)4/h3-4H,1-2H3 Key: KJRCEJOSASVSRA-UHFFFAOYSA-N;
	SMILES CC(C)S;
Properties
Chemical formula	C3H8S
Molar mass	76.16 g·mol−1
Density	0.8143
Melting point	−130.7 °C (−203.3 °F; 142.5 K)
Boiling point	52.5 °C (126.5 °F; 325.6 K)
Solubility in water	4835 g/L
Vapor pressure	277.3 mm Hg
Hazards
	GHS labelling:
Pictograms
Signal word	Danger
Hazard statements	H225, H302, H315, H319, H331
Precautionary statements	P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P316, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, P501
Related compounds
Related compounds	Propanethiol
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Isopropyl mercaptan is an organic compound with the formula C₃H₈S. It has the CAS Registry Number 75-33-2.^[2] It is REACH registered with the European number of 200-861-4.^[3] It is a water-white liquid with an extremely pungent odor resembling skunk spray or bad eggs. The odor means one use is as an odorizer.^[4] Despite this, it has Food and Drug Administration sanction as a food additive to add flavor.^[5] Another use is as a rubber additive.^[6]

Analysis and detection

The usual method of analysis and detection is by gas chromatography.^[7]^[8]

References

^ "2-Propanethiol". pubchem.ncbi.nlm.nih.gov.
^ "CAS Common Chemistry". commonchemistry.cas.org. Retrieved 2023-09-15.
^ PubChem. "2-Propanethiol". pubchem.ncbi.nlm.nih.gov. Retrieved 2023-09-15.
^ Michanowicz, Drew R.; Leventhal, Olivia M.; Domen, Jeremy K.; Williams, Samuel R.; Lebel, Eric D.; Hill, Lee Ann L.; Buonocore, Jonathan J.; Nordgaard, Curtis L.; Bernstein, Aaron S.; Shonkoff, Seth B.C. (2023-07-25). "Natural gas odorants: A scoping review of health effects". Current Environmental Health Reports. 10 (3): 337–352. doi:10.1007/s40572-023-00403-w. ISSN 2196-5412. PMC 10504204. PMID 37491689. S2CID 260163457.
^ PubChem. "2-Propanethiol Flavor profile". pubchem.ncbi.nlm.nih.gov. Retrieved 2023-09-15.
^ Li, Zhiwei; An, Dong; He, Rizheng; Sun, Zhijian; Li, Jiaxiong; Zhang, Zhiyi; Liu, Yaqing; Wong, Chingping (April 2023). "The design of crosslinks in different vulcanized systems to improve crack growth resistance for carbon black/graphene oxide/natural rubber composites". Advanced Composites and Hybrid Materials. 6 (2). doi:10.1007/s42114-023-00662-z. ISSN 2522-0128. S2CID 258137193.
^ Tangerman, Albert (1986-01-01). "Determination of volatile sulphur compounds in air at the parts per trillion level by tenax trapping and gas chromatography". Journal of Chromatography A. 366: 205–216. doi:10.1016/S0021-9673(01)93468-5. ISSN 0021-9673. PMID 3782318.
^ Wang, Xinguang; Le, Minh; Stuetz, Richard (January 2022). "Calibration methods for VSCs measured on AS-TD-GC-SCD". Environmental Monitoring and Assessment. 194 (1): 25. doi:10.1007/s10661-021-09690-y. ISSN 0167-6369. PMID 34905118. S2CID 245134350.

[1] "2-Propanethiol". pubchem.ncbi.nlm.nih.gov.

[2] "CAS Common Chemistry". commonchemistry.cas.org. Retrieved 2023-09-15.

[3] PubChem. "2-Propanethiol". pubchem.ncbi.nlm.nih.gov. Retrieved 2023-09-15.

[4] Michanowicz, Drew R.; Leventhal, Olivia M.; Domen, Jeremy K.; Williams, Samuel R.; Lebel, Eric D.; Hill, Lee Ann L.; Buonocore, Jonathan J.; Nordgaard, Curtis L.; Bernstein, Aaron S.; Shonkoff, Seth B.C. (2023-07-25). "Natural gas odorants: A scoping review of health effects". Current Environmental Health Reports. 10 (3): 337–352. doi:10.1007/s40572-023-00403-w. ISSN 2196-5412. PMC 10504204. PMID 37491689. S2CID 260163457.

[5] PubChem. "2-Propanethiol Flavor profile". pubchem.ncbi.nlm.nih.gov. Retrieved 2023-09-15.

[6] Li, Zhiwei; An, Dong; He, Rizheng; Sun, Zhijian; Li, Jiaxiong; Zhang, Zhiyi; Liu, Yaqing; Wong, Chingping (April 2023). "The design of crosslinks in different vulcanized systems to improve crack growth resistance for carbon black/graphene oxide/natural rubber composites". Advanced Composites and Hybrid Materials. 6 (2). doi:10.1007/s42114-023-00662-z. ISSN 2522-0128. S2CID 258137193.

[7] Tangerman, Albert (1986-01-01). "Determination of volatile sulphur compounds in air at the parts per trillion level by tenax trapping and gas chromatography". Journal of Chromatography A. 366: 205–216. doi:10.1016/S0021-9673(01)93468-5. ISSN 0021-9673. PMID 3782318.

[8] Wang, Xinguang; Le, Minh; Stuetz, Richard (January 2022). "Calibration methods for VSCs measured on AS-TD-GC-SCD". Environmental Monitoring and Assessment. 194 (1): 25. doi:10.1007/s10661-021-09690-y. ISSN 0167-6369. PMID 34905118. S2CID 245134350.

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Analysis and detection

See also

References