Burkholderia thailandensis
| Burkholderia thailandensis | |
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| Burkholderia thailandensis on Ashdown's media | |
Scientific classification 
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| Domain: | Bacteria |
| Phylum: | Pseudomonadota |
| Class: | Betaproteobacteria |
| Order: | Burkholderiales |
| Family: | Burkholderiaceae |
| Genus: | Burkholderia |
| Species: | B. thailandensis
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| Binomial name | |
| Burkholderia thailandensis Brett et al. 1998[1]
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Burkholderia thailandensis is a nonfermenting motile, Gram-negative bacillus that occurs naturally in soil. It is closely related to Burkholderia pseudomallei, but unlike B. pseudomallei, it only rarely causes disease in humans or animals.[2][3][4][5] The lethal inoculum is approximately 1000 times higher than for B. pseudomallei.[6] It is usually distinguished from B. pseudomallei by its ability to assimilate arabinose.[7] Other differences between these species include lipopolysaccharide composition, colony morphology, and differences in metabolism.[8]
Use in research
[edit]Burkholderia thailandensis is sometimes used to model B. pseudomallei infection in mice because of similarities in the immune response.[9][10][11] B. thailandensis does not require biosafety category 3 facilities and is not considered a biosecurity threat, which makes it easier to study and to work with.[12] Burkholderia thailandensis has secondary products that play an essential role in the ecology of soil bacteria.[13] Co-culture studies showed that B. thailandensis strain E264 produces an antimicrobial substance that prevents the growth of other soil bacteria called Bacillus subtilis strain 168.
Small RNA
[edit]Research suggests that as in other bacteria, small non coding RNAs play a role in response to the environmental and stress conditions like antibiotic exposure and survival in a host-specific environment.[14] Several small RNA have been discovered in B. thailandenisis: BHT_s1 and BHT_s39 exhibit differential expression profiles dependent on growth phase and cell stimuli, such as antibiotics and serum. BHT_s39 could function in bacterial metabolism and adaptation to host. BTH_s13 and BTH_s19 may regulate expression of their downstream gene.[14]
References
[edit]- ^ Brett PJ, DeShazer D, Woods DE (1998). "Burkholderia thailandensis sp. nov., a Burkholderia pseudomallei-like species". Int J Syst Bacteriol. 48: 317–320. doi:10.1099/00207713-48-1-317. PMID 9542103.
- ^ Wuthiekanun V, Smith MD, Dance DA, Walsh AL, Pitt TL, White NJ (1996). "Biochemical characteristics of clinical and environmental isolates of Burkholderia pseudomallei". J Med Microbiol. 45 (6): 408–12. doi:10.1099/00222615-45-6-408. PMID 8958243.
- ^ Smith MD, Angus BJ, Wuthiekanun V, White NJ (1997). "Arabinose assimilation defines a nonvirulent biotype of Burkholderia pseudomallei". Infect Immun. 65 (10): 4319–21. doi:10.1128/IAI.65.10.4319-4321.1997. PMC 175618. PMID 9317042.
- ^ Lertpatanasuwan N, Sermsri K, Petkaseam A, Trakulsomboon S, Thamlikitkul V, Suputtamongkol Y (1999). "Arabinose-positive Burkholderia pseudomallei infection in humans: case report". Clin Infect Dis. 28 (4): 927–28. doi:10.1086/517253. PMID 10825075.
- ^ Glass MB, Gee JE, Steigerwalt AG, et al. (2006). "Pneumonia and Septicemia Caused by Burkholderia thailandensis in the United States". J Clin Microbiol. 44 (12): 4601–04. doi:10.1128/JCM.01585-06. PMC 1698378. PMID 17050819.
- ^ Wiersinga WJ, de Vos AF, de Beer R, et al. (2007). "Inflammation patterns induced by different Burkholderia species in mice". Cell Microbiol. 10 (1): 81–87. doi:10.1111/j.1462-5822.2007.01016.x. PMID 17645551. S2CID 22030395.
- ^ Smith MD, Angus BJ, Wuthiekanun V, White NJ (1997). "Arabinose assimilation defines a nonvirulent biotype of Burkholderia pseudomallei". Infect Immun. 65 (10): 4319–321. doi:10.1128/IAI.65.10.4319-4321.1997. PMC 175618. PMID 9317042.
- ^ Woods DE (1999). "Species versus Biotype Status". J Clin Microbiol. 37 (11): 3786–7. doi:10.1128/JCM.37.11.3786-3787.1999. PMC 85768. PMID 10610379.
- ^ Wiersinga WJ, de Vos AF, de Beer R, Wieland CW, Roelofs JJTH, Woods DE (2008). "Inflammation patterns induced by different Burkholderia species in mice". Cell Microbiol. 10 (1): 81–7. doi:10.1111/j.1462-5822.2007.01016.x. PMID 17645551. S2CID 22030395.
- ^ Haraga A, West TE, Brittnacher MJ, Skerrett SJ, Miller SI (2008). "Burkholderia thailandensis as a model system for the Study of the virulence-associated type III secretion system of Burkholderia pseudomallei". Infect Immun. 76 (11): 5402–11. doi:10.1128/IAI.00626-08. PMC 2573339. PMID 18779342.
- ^ Morici LA, Heang J, Tate T, Didier PJ, Roy CJ (2010). "Differential susceptibility of inbred mouse strains to Burkholderia thailandensis aerosol infection". Microb Pathog. 48 (1): 9–17. doi:10.1016/j.micpath.2009.10.004. PMC 7006035. PMID 19853031.
- ^ Haraga A, West TE, Brittnacher MJ, Skerrett SJ, Miller SI (2008). "Burkholderia thailandensis as a Model System for the Study of the Virulence-Associated Type III Secretion System of Burkholderia pseudomallei". Infect Immun. 76 (11): 5402–11. doi:10.1128/IAI.00626-08. PMC 2573339. PMID 18779342.
- ^ Klaus, J. R., Majerczyk, C., Moon, S., Eppler, N. A., Smith, S., Tuma, E., Groleau, M.C., Asfahl, K. L., & Smalley, N. E., Nicole, E., Hayden, H. S., Piochon, M., Ball, P., Dandekar, A. A., Gauthier, C., Deziel, E., Chandler, J. R. (2020). Burkholderia thailandensis methylated hydroxyalkylquinolines: Biosynthesis and antimicrobial activity in cocultures. Applied and Environmental Microbiology, 86(24), 1-17. doi:10.1128/AEM.01452-20
- ^ a b Stubben, Chris J.; Micheva-Viteva, Sofiya N.; Shou, Yulin; Buddenborg, Sarah K.; Dunbar, John M.; Hong-Geller, Elizabeth (2014-05-19). "Differential expression of small RNAs from Burkholderia thailandensis in response to varying environmental and stress conditions". BMC Genomics. 15 (1): 385. doi:10.1186/1471-2164-15-385. ISSN 1471-2164. PMC 4035088. PMID 24884623.
External links
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