Heavy meromyosin
Appearance
Heavy meromyosin (HMM) is the larger of the two fragments obtained from the muscle protein myosin II following limited proteolysis by trypsin or chymotrypsin.[1] HMM contains two domains S-1 and S-2, S-1 contains is the globular head that can bind to actin while the S-2 domain projects at and angle from light meromyosin (LMM) connecting the two meromyosin fragments.[2]
HMM is used to determine the polarity of actin filaments by decorating them with HMM then viewing them under the electron microscope.[1]
References
- ^ a b "Answers - The Most Trusted Place for Answering Life's Questions". Answers.com. Retrieved 2018-01-24.
- ^ "Heavy meromyosin - an overview | ScienceDirect Topics". www.sciencedirect.com. Retrieved 2018-01-24.