Angiomyofibroblastoma
 | This article may be too technical for most readers to understand. (May 2014) |
Angiomyofibroblastoma is an uncommon benign mesenchymal tumor. It occurs almost in the vulvovaginal area of women, but can also be observed in men.
The gross features of AMFB are well-circumscribed. Usually, most tumors grow slowly, and patients do not feel pain. It also has low tendency for local recurrence.
Location
- In women
- In men
Pathology
Microscopical examination shows abundant thin-walled blood vessels with hypocellular and hypercellular areas.
Immunohistochemistry
Almost all tumor cells have immunoreactivity for both desmin and vimentin. It also express estrogen receptors and/or progesterone receptors, but staining for cytokeratin is negative.[5]
References
- ^ Wang, J; Sheng, W; Tu, X; Shi, D; Zhu, X; Zhang, R (2000). "Clinicopathologic analysis of angiomyofibroblastoma of the female genital tract". Chinese Medical Journal. 113 (11): 1036–9. PMID 11776120.
- ^ Seo, J. W.; Lee, K. A.; Yoon, N. R.; Lee, J. W.; Kim, B. G.; Bae, D. S. (2013). "Angiomyofibroblastoma of the vulva". Obstetrics & Gynecology Science. 56 (5): 349–51. doi:10.5468/ogs.2013.56.5.349. PMC 3784123. PMID 24328028.
- ^ Lim, K. J.; Moon, J. H.; Yoon, D. Y.; Cha, J. H.; Lee, I. J.; Min, S. J. (2008). "Angiomyofibroblastoma arising from the posterior perivesical space: A case report with MR findings". Korean Journal of Radiology. 9 (4): 382–5. doi:10.3348/kjr.2008.9.4.382. PMC 2627271. PMID 18682679.
- ^ Tzanakis, N. E.; Giannopoulos, G. A.; Efstathiou, S. P.; Rallis, G. E.; Nikiteas, N. I. (2010). "Angiomyofibroblastoma of the spermatic cord: A case report". Journal of Medical Case Reports. 4: 79. doi:10.1186/1752-1947-4-79. PMC 2838917. PMID 20202207.
{{cite journal}}: CS1 maint: unflagged free DOI (link) - ^ Seo, J. W.; Lee, K. A.; Yoon, N. R.; Lee, J. W.; Kim, B. G.; Bae, D. S. (2013). "Angiomyofibroblastoma of the vulva". Obstetrics & Gynecology Science. 56 (5): 349–51. doi:10.5468/ogs.2013.56.5.349. PMC 3784123. PMID 24328028.
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