Arrakis Therapeutics
Arrakis Therapeutics is a Waltham, Massachusetts-based biotechnology company developing drugs for neurological disorders and other diseases. The company was co-founded in 2015 by CEO Michael Gilman[1], a former Biogen executive who co-founded and led Padlock Therapeutics (bought out by Bristol-Myers Squibb in 2016) and Stromedix (acquired by Biogen Idec in 2012).[2]
Named after the desert world in Frank Herbert’s science fiction classic Dune, Arrakis will use small-molecule medicinal chemistry to target RNA. While there are already approved drugs based on RNA-targeting molecules, they have been found by accident whereas Arrakis intends to take a systematic approach, Gilman says.[3] The company claims a bioinformatic tool will allow its scientists to identify sites on RNA that can bind small molecules, while another set of chemical biology tools will allow researchers to validate the molecules’ efficacy and selectivity. In addition to neurology, Arrakis will also target cancer and rare genetic diseases.[4]
In February 2017, Arrakis received a $38.5 million Series A round from investors including pharmaceutical giants Celgene and Pfizer.[5]
References
- ^ www.bizjournals.com https://www.bizjournals.com/boston/news/2019/01/14/vc-firm-atlas-ditches-jp-morgan-conference-will.html. Retrieved 2019-02-15.
{{cite web}}: Missing or empty|title=(help) - ^ "Arrakis Raises $38M in Series A Financing and Names Michael Gilman as CEO | GEN Genetic Engineering & Biotechnology News - Biotech from Bench to Business | GEN". GEN. Retrieved 2017-04-17.
- ^ "Pfizer, Celgene-backed upstart Arrakis hopes to mine RNA spice | FierceBiotech". www.fiercebiotech.com. Retrieved 2017-04-17.
- ^ Jarvis, Lisa M. "Arrakis launches to develop RNA-targeting small-molecule drugs | Chemical & Engineering News". cen.acs.org. Retrieved 2017-04-17.
- ^ "At Arrakis, Gilman Teams With Biogen Vets to Target RNA With Pills | Xconomy". Xconomy. 2017-02-27. Retrieved 2017-04-17.