Craig plot
The Craig plot, named after Paul N. Craig, is a plot of two substituent parameters (e.g. Hansch-Fujita π constant and sigma constant) used in rational drug design.[1]
Two most used forms of a Craig plot are
- plotting the sigma constants of the Hammett equation versus hydrophobicity
- plotting the steric terms of the Taft equation against hydrophobicity
See also
References
- ^ "IUPAC glossary". Archived from the original on 2006-12-09. Retrieved 2006-12-14.
Further reading
- Craig, Paul N. "Interdependence between physical parameters and selection of substituent groups for correlation studies". Journal of Medicinal Chemistry. 14: 680–684. doi:10.1021/jm00290a004.
 | This organic chemistry article is a stub. You can help Wikipedia by expanding it. |