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Craig plot

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Craig plot showing values of Hansch pi and Hammett sigma constants for 26 common organic substituents

The Craig plot, named after Paul N. Craig, is a plot of two substituent parameters (e.g. Hansch-Fujita π constant and sigma constant) used in rational drug design.[1]

Two most used forms of a Craig plot are

See also

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References

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  1. ^ "IUPAC glossary". Archived from the original on 2006-12-09. Retrieved 2006-12-14.

Further reading

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  • Craig, Paul N. (1971). "Interdependence between physical parameters and selection of substituent groups for correlation studies". Journal of Medicinal Chemistry. 14 (8): 680–684. doi:10.1021/jm00290a004. PMID 5114063.