Metazosin

Metazosin
Names
	IUPAC name 1-[4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-2-methoxypropan-1-one
	Other names Kenosin
Identifiers
CAS Number	95549-92-1;
3D model (JSmol)	Interactive image;
ChemSpider	84417;
PubChem CID	93514;
CompTox Dashboard (EPA)	DTXSID50878352 DTXSID00275913, DTXSID50878352 ;
	InChI InChI=1S/C18H25N5O4/c1-11(25-2)17(24)22-5-7-23(8-6-22)18-20-13-10-15(27-4)14(26-3)9-12(13)16(19)21-18/h9-11H,5-8H2,1-4H3,(H2,19,20,21) Key: YEOTYALSMRNXLJ-UHFFFAOYSA-N;
	SMILES CC(C(=O)N1CCN(CC1)C2=NC3=CC(=C(C=C3C(=N2)N)OC)OC)OC;
Properties
Chemical formula	C18H25N5O4
Molar mass	375.429 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Metazosin is an antihypertensive alpha-adrenergic antagonist.^[1]^[2]

References

^ Trcka, V; König, J; Mácová, S; Smíd, M; Helfert, I; Votavová, M; Remesová, J; Nezádalová, E (1990). "Pharmacology of a new antihypertensive agent, metazosin (Kenosin)". Ceskoslovenska farmacie. 39 (6): 266–74. PMID 1981860.
^ Lapka, R; Rejholec, V; Sechser, T; Peterková, M; Smíd, M (1989). "Interspecies pharmacokinetic scaling of metazosin, a novel alpha-adrenergic antagonist". Biopharmaceutics & drug disposition. 10 (6): 581–9. PMID 2575403.

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