Isoniazid/rifampicin
| Combination of | |
|---|---|
| Isoniazid | Anti-tuberculosis medication |
| Rifampicin | Anti-tuberculosis medication |
| Clinical data | |
| Trade names | IsonaRif, Rifamate, others |
| ATC code | |
| Identifiers | |
| KEGG | |
Isoniazid/rifampicin, also known as isoniazid/rifampin, is a medication used to treat tuberculosis.[1] It is a fixed dose combination of isoniazid and rifampicin (rifampin).[1] It is used together with other antituberculosis medication.[1] It is taken by mouth.[1]
Side effects are those of the underlying medications.[1] Common side effects include poor coordination, poor appetite, nausea, numbness, and feeling tired.[2] More severe side effects include liver problems.[2] Use is generally not recommended in children.[1] It is unclear if use is safe in pregnancy.[3]
It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system.[4] The wholesale cost in the developing world is about US$5.10 a month.[5] In the United Kingdom a month of medication costs the NHS about 28.11 pounds.[6]
References
- ^ a b c d e f World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. p. 142. hdl:10665/44053. ISBN 9789241547659.
- ^ a b "Isoniazid/rifampin Side Effects in Detail - Drugs.com". www.drugs.com. Archived from the original on 21 December 2016. Retrieved 18 December 2016.
- ^ "Isoniazid / rifampin Use During Pregnancy | Drugs.com". www.drugs.com. Archived from the original on 21 December 2016. Retrieved 18 December 2016.
- ^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
- ^ "Rifampicin + Isoniazid". International Drug Price Indicator Guide. Retrieved 8 December 2016.
- ^ British national formulary : BNF 69 (69 ed.). British Medical Association. 2015. p. 403. ISBN 9780857111562.
