List of universities in North Carolina by enrollment
This list of largest North Carolina higher education institutions by enrollment includes only individual four-year campuses, not four-year universities. Universities can have multiple campuses with a single administration. Enrollment numbers listed are the sum of undergraduate and graduate students. These numbers should match the enrollment numbers that are reported to the US Department of Education.
| Top 10 as of Fall 2019 | |||
| Ranking | University | Location | Enrollment |
| 1 | North Carolina State University | Raleigh, North Carolina | 34,015 |
| 2 | University of North Carolina at Chapel Hill | Chapel Hill, NC | 29,469 |
| 3 | University of North Carolina at Charlotte | Charlotte, North Carolina | 29,000 |
| 4 | East Carolina University | Greenville, North Carolina | 28,962 |
| 5 | University of North Carolina at Greensboro | Greensboro, NC | 20,106 |
| 6 | Appalachian State University | Boone, NC | 19,108 |
| 7 | University of North Carolina at Wilmington | Wilmington, NC | 16,747 |
| 8 | Duke University | Durham, North Carolina | 15,892 |
| 9 | North Carolina A&T State University | Greensboro, NC | 12,142 |
| 10 | Western Carolina University | Cullowhee, NC | 11,639 |