Jump to content

Karla Satchell

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by 24.148.4.163 (talk) at 23:34, 11 April 2020. The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Karla Satchell is an American microbiologist who is currently a professor at Northwestern University Feinberg School of Medicine[1] and an elected fellow of the American Association for the Advancement of Science.[2] She serves as an acting fill-in anchor for WGN-TV in Chicago, Illinois.

Education

She earned her Ph.D at University of Washington in 1996 and conducted postdoctoral training with John Mekalanos at Harvard Medical School.[1]

Research

Her interests are bacteriology, structural biology, and immunology,[3] cytoskeleton, cellular microbiology, bacteria and diseases[4] and pathogenesis.[1] She is especially known for defining how the MARTX toxin in Vibrio cholerae is a modular protein that delivers its constituent effectors to host cells.[5]

Immunology

Satchell is head of the Center for Structural Genomics of Infectious Diseases at Northwestern. The Center, established in 2007, provides an established consortium of laboratories in North America for rapid response research related to infectious disease outbreaks. It maps and examines the genomes of disease causing agents such as viruses to establish effective treatments.[6]

Publications

  • Kerri-Lynn Sheahan, Christina L. Cordero, and Karla J. Fullner Satchell. Identification of a domain within the multifunctional Vibrio cholerae RTX toxin that covalently cross-links actin. PNAS. vol. 101 no. 26. 9798–9803
  • KJF Satchell. MARTX, multifunctional autoprocessing repeats-in-toxin toxins. Infection and immunity. November 2007 vol. 75 no. 11 5079-5084.

References

  1. ^ a b c "Karla Satchell". northwestern.edu. Retrieved December 27, 2017.
  2. ^ "Elected AAAS Fellows". northwestern.edu. December 13, 2016. Retrieved December 27, 2017.
  3. ^ "Lab". satchell-lab.com. Retrieved December 27, 2017.
  4. ^ "Karla Satchell". northwestern.edu. Retrieved December 27, 2017.
  5. ^ Satchell, Karla J. F. (25 June 2015). "Multifunctional-autoprocessing repeats-in-toxin (MARTX) Toxins of Vibrios". Microbiology Spectrum. 3 (3). doi:10.1128/microbiolspec.VE-0002-2014. PMC 4509488. PMID 26185092.
  6. ^ Rhodes, Dawn (January 24, 2020). "Northwestern University professor leading research team trying to stop coronavirus: 'We are here specifically for this.'". Chicago Tribune. Retrieved 2020-01-28.