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Cryptolepis sanguinolenta

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Cryptolepis sanguinolenta
Scientific classification Edit this classification
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Asterids
Order: Gentianales
Family: Apocynaceae
Genus: Cryptolepis
Species:
C. sanguinolenta
Binomial name
Cryptolepis sanguinolenta
(Lindl.) Schltr.

Cryptolepis sanguinolenta is a species of flowering plant in the family Apocynaceae. An extract from the root is traditionally used in West Africa for malaria.[1][2]

It contains the alkaloids cryptolepine, quindoline, and neocryptolepine.[3][unreliable source?]

The roots are also used as a yellow dye.

In a microbiological study at Johns Hopkins University, an ethanolic (60%) extract of Cryptolepis sanguinolenta was found highly active in-vitro against stationary phase B. burgdorferi.[4]


References

  1. ^ Tempesta, M. S (2010). "The Clinical Efficacy of Cryptolepis Sanguinolenta in the Treatment of Malaria". Ghana Medical Journal. 44 (1): 1–2. PMC 2956313. PMID 21326982.
  2. ^ Ansah, C (2002). "The Popular Herbal Antimalarial, Extract of Cryptolepis sanguinolenta, is Potently Cytotoxic". Toxicological Sciences. 70 (2): 245–251. doi:10.1093/toxsci/70.2.245.
  3. ^ Buhner, S. H. (1999). Herbal Antibiotics: Natural Alternatives for Treating Drug-Resistant Bacteria. Storey Publishing.
  4. ^ Feng J., Leone J., Schweig S., Zhang Y.: Evaluation of Natural and Botanical Medicines for Activity Against Growing and Non-growing Forms of B. burgdorferi, Front. Med. 21 February 2020; doi.org/10.3389/fmed.2020.00006