XhoI

Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

XhoI
XhoI
Identifiers
Symbol	XhoI
Pfam	PF04555
InterPro	IPR007636
Pfam
Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

In molecular biology, XhoI is a type II restriction enzyme EC that recognise the double-stranded DNA sequence CTCGAG and cleaves after C-1.^[1] Type II restriction endonucleases (EC) are components of prokaryotic DNA restriction-modification mechanisms that protect the organism against invading foreign DNA. These site-specific deoxyribonucleases catalyse the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.

References

^ Theriault G, Roy PH, Howard KA, Benner JS, Brooks JE, Waters AF, Gingeras TR (December 1985). "Nucleotide sequence of the PaeR7 restriction/modification system and partial characterization of its protein products". Nucleic Acids Res. 13 (23): 8441–61. doi:10.1093/nar/13.23.8441. PMC 322144. PMID 3001639.

This article incorporates text from the public domain Pfam and InterPro: IPR007636

[pmid3001639-1] Theriault G, Roy PH, Howard KA, Benner JS, Brooks JE, Waters AF, Gingeras TR (December 1985). "Nucleotide sequence of the PaeR7 restriction/modification system and partial characterization of its protein products". Nucleic Acids Res. 13 (23): 8441–61. doi:10.1093/nar/13.23.8441. PMC 322144. PMID 3001639.

[1]

v t e Restriction modification system: restriction enzyme
Basic Concept	Isoschizomer Neoschizomer Isocaudomer
Recognition sequence 4bp	TaqI Sau3A AluI* HaeIII* DpnII NlaIII HpaII
Recognition sequence 5bp	EcoRII FokI
Recognition sequence 6bp	AaaI BglII PovII* EcoRV* EcoRI BamHI HindIII XbaI XhoI SacI PstI NdeI
Recognition sequence 8bp	NotI
Lists	A Ba–Bc Bd–Bp Bsa–Bso Bsp–Bss Bst–Bv C-D E-F G-K L-N O-R S T-Z
* means cleavage produces blunt ends