Ion transporter superfamily
| Identifiers | |
|---|---|
| Symbol | IT |
| Pfam clan | CL0182 |
| OPM superfamily | 272 |
| OPM protein | 4r1i |
The ion transporter (IT) superfamily is a superfamily of secondary carriers that transport charged substrates.[1][2]
Families
As of early 2016, the currently recognized and functionally defined families that make up the IT superfamily include:
- 2.A.8 - The Gluconate:H+ Symporter (GntP) Family
- 2.A.11 - The Citrate-Mg2+:H+ (CitM) Citrate-Ca2+:H+ (CitH) Symporter (CitMHS) Family
- 2.A.13 - The C4-Dicarboxylate Uptake (Dcu) Family
- 2.A.14 - The Lactate Permease (LctP) Family
- 2.A.34 - The NhaB Na+:H+ Antiporter (NhaB) Family
- 2.A.35 - The NhaC Na+:H+ Antiporter (NhaC) Family
- 2.A.45 - The Arsenite-Antimonite (ArsB) Efflux Family
- 2.A.47 - The Divalent Anion:Na+ Symporter (DASS) Family
- 2.A.61 - The C4-dicarboxylate Uptake C (DcuC) Family
- 2.A.62 - The NhaD Na+:H+ Antiporter (NhaD) Family
- 2.A.68 - The p-Aminobenzoyl-glutamate Transporter (AbgT) Family
- 2.A.94 - The Phosphate Permease (Pho1) Family
- 2.A.101 - The Malonate Uptake (MatC) Family
- 2.A.111 - The Na+/H+ Antiporter-E (NhaE) Family
- 2.A.118 - The Basic Amino Acid Antiporter (ArcD) Family
See also
- Ion transporters
- Sodium-Proton antiporter
- Arsenite-Antimonite efflux
- Amino acid transporter
- Solute carrier family
- Transporter Classification Database
- Membrane protein
References
- ^ Prakash S, Cooper G, Singhi S, Saier MH (December 2003). "The ion transporter superfamily". Biochimica et Biophysica Acta (BBA) - Biomembranes. 1618 (1): 79–92. doi:10.1016/j.bbamem.2003.10.010. PMID 14643936.
- ^ Chen JS, Reddy V, Chen JH, Shlykov MA, Zheng WH, Cho J, Yen MR, Saier MH (2011-01-01). "Phylogenetic characterization of transport protein superfamilies: superiority of SuperfamilyTree programs over those based on multiple alignments". Journal of Molecular Microbiology and Biotechnology. 21 (3–4): 83–96. doi:10.1159/000334611. PMC 3290041. PMID 22286036.
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