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Alanosine

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Alanosine
Skeletal formula of L-alanosine
Ball-and-stick model of the L-alanosine molecule as a zwitterion
Clinical data
ATC code
  • None
Identifiers
  • (S)-2-Amino-3-[hydroxy(nitroso)amino]propanoic acid
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC3H7N3O4
Molar mass149.106 g·mol−1
3D model (JSmol)
  • O=C(O)[C@@H](N)CN(O)N=O
  • InChI=1S/C3H7N3O4/c4-2(3(7)8)1-6(10)5-9/h2,10H,1,4H2,(H,7,8)/t2-/m0/s1 checkY
  • Key:MLFKVJCWGUZWNV-REOHCLBHSA-N checkY
  (verify)

Alanosine (also called SDX-102) is a substance that is being studied for the treatment of pancreatic cancer.[1] It is an antimetabolite. It is used as one of a few experimental treatments for patients with deadly pancreatic cancer when the main chemotherapeutic treatment regimen of gemcitabine is no longer useful.

References

  1. ^ Yu J (2001). "Alanosine (UCSD)". Curr Opin Investig Drugs. 2 (11): 1623–30. PMID 11763167.


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