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Methylenomycin B

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Methylenomycin B
Structural formula of methylenomycin B
Ball-and-stick model of the methylenomycin B molecule
Names
IUPAC name
2,3-Dimethyl-5-methylene-2-cyclopenten-1-one
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C8H10O/c1-5-4-6(2)8(9)7(5)3/h2,4H2,1,3H3 checkY
    Key: YDXIEAHUYZKJOH-UHFFFAOYSA-N checkY
  • InChI=1/C8H10O/c1-5-4-6(2)8(9)7(5)3/h2,4H2,1,3H3
    Key: YDXIEAHUYZKJOH-UHFFFAOYAN
  • O=C/1\C(=C)CC(=C\1C)\C
Properties
C8H10O
Molar mass 122.167 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)

Methylenomycin B is a cyclopentanone derived antibiotic produced by Streptomyces coelicolor A3(2) that is effective against both Gram-negative and Gram-positive bacteria.[1][2] Methylenomycins are naturally produced in two variants: A and B.

See also

References

  1. ^ Brian P, Riggle PJ, Santos RA, Champness WC (June 1996). "Global negative regulation of Streptomyces coelicolor antibiotic synthesis mediated by an absA-encoded putative signal transduction system". J. Bacteriol. 178 (11): 3221–31. doi:10.1128/jb.178.11.3221-3231.1996. PMC 178074. PMID 8655502.
  2. ^ Hobbs G, Obanye AI, Petty J, et al. (March 1992). "An integrated approach to studying regulation of production of the antibiotic methylenomycin by Streptomyces coelicolor A3(2)". J. Bacteriol. 174 (5): 1487–94. PMC 206543. PMID 1537793.


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