Catharanthine
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Other names
Methyl(5|A)-3,4-didehydroibogamine-18-carboxylate
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Identifiers | |
3D model (JSmol)
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ChEBI | |
ChemSpider | |
ECHA InfoCard | 100.017.806 |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C21H24N2O2 | |
Molar mass | 336.435 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Catharanthine is a terpene indole alkaloid produced by the medicinal plant Catharanthus roseus and Tabernaemontana_divaricata. Catharanthine is derived from strictosidine, but the exact mechanism by which this happens is currently unknown. Catharanthine is one of the two precursors that form vinblastine, the other being vindoline.
Uses
Modern Medicine
It showed anti-tumorogenic effect as well as inhibited cAMP phosphodiesterase activity [1]It increased the intracellular level of cAMP in neurons and thus may lead to improved neuronal activity [2]