Cocaine (data page)
This page provides supplementary chemical data on Cocaine in free base form. More commonly available "powder cocaine" is a hydrochloride salt whose properties will differ.
Material Safety Data Sheet
The handling of this chemical may incur notable safety precautions. It is highly recommend that you seek the Material Safety Datasheet (MSDS) for this chemical from a reliable source such as SIRI, and follow its directions.
Structure and properties
| Structure and properties | |
|---|---|
| Index of refraction, nD | 1.5022 [1] |
| Abbe number | ? |
| Dielectric constant, εr | ? ε0 at ? °C |
| Bond strength | ? |
| Bond length | ? |
| Bond angle | ? |
| Magnetic susceptibility | ? |
| Melting point | 98 °C [1] |
| Boiling point | 187 °C [1] |
| Solubility | 1.7 g/L at 25 °C [1] |
Thermodynamic properties
| Phase behavior | |
|---|---|
| Triple point | ? K (? °C), ? Pa |
| Critical point | ? K (? °C), ? Pa |
| Std enthalpy change of fusion, ΔfusH |
? kJ/mol |
| Std entropy change of fusion, ΔfusS |
? J/(mol·K) |
| Std enthalpy change of vaporization, ΔvapH |
? kJ/mol |
| Std entropy change of vaporization, ΔvapS |
? J/(mol·K) |
| Solid properties | |
| Std enthalpy change of formation, ΔfH |
? kJ/mol |
| Standard molar entropy, S |
? J/(mol K) |
| Specific heat capacity, cp | ? J/(mol K) |
| Liquid properties | |
| Std enthalpy change of formation, ΔfH |
? kJ/mol |
| Standard molar entropy, S |
? J/(mol K) |
| Specific heat capacity, cp | ? J/(mol K) |
| Gas properties | |
| Std enthalpy change of formation, ΔfH |
? kJ/mol |
| Standard molar entropy, S |
? J/(mol K) |
| Specific heat capacity, cp | ? J/(mol K) |
Spectral data
| UV-Vis | |
|---|---|
| λmax | ? nm |
| Extinction coefficient, ε | ? |
| IR | |
| Major absorption bands | ? cm−1 |
| NMR | |
| Proton NMR | |
| Carbon-13 NMR | |
| Other NMR data | |
| MS | |
| Masses of main fragments |
|
External links
- Nuclear magnetic resonance and molecular orbital study of some cocaine analogues, includes superposition and overlay of cocaine, cocaine derivatives, and their minimum energy values.
- Conformational changes in dopamine transporter intracellular regions upon cocaine binding and dopamine translocation, thorough-going elucidation of exact mechanism and mode of action specific to cocaine at the dopamine transporter.
- Genome Wide Analysis of Chromatin Regulation by Cocaine Reveals a Novel Role for Sirtuins
References
Except where noted otherwise, data relate to standard ambient temperature and pressure.
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