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A16, A 16 A.16 or A-16 may refer to:

It may also refer to:

  • A16, a restaurant in the San Francisco Bay Area
  • Subfamily A16, a rhodopsin-like receptors sub family
  • One of the Encyclopaedia of Chess Openings codes for the English Opening in chess
  • Washington A16, 2000 Protests in Washington, D.C. against the International Monetary Fund and the World Bank on April 16 of 2000 and 2005, both known as "A16"