AP20187

From Wikipedia, the free encyclopedia
Jump to navigation Jump to search

AP20187 is a ligand that can induce homodimerization of fusion proteins containing the F36V mutant of an FKBP domain(FKBPF36V),[1] available commercially as the DmrB domain.[2][3]

References[edit]

  1. ^ Kawahara, Masahiro; Mabe, Satoru; Nagamune, Teruyuki. "Detecting protein–protein interactions based on kinase-mediated growth induction of mammalian cells". Scientific Reports. 4: 6127. doi:10.1038/srep06127. PMC 4137342.
  2. ^ "Dimerizer Ligands - B/B Homodimerizer (AP20187), A/C Heterodimerizer (AP21967), D/D Solubilizer (AP21998), B/B Washout Ligand". Clontech.com. Retrieved February 5, 2016.
  3. ^ Cotugno, G; Formisano, P; Giacco, F; Colella, P; Beguinot, F; Auricchio, A. "AP20187-mediated activation of a chimeric insulin receptor results in insulin-like actions in skeletal muscle and liver of diabetic mice". Hum Gene Ther. 18: 106–17. doi:10.1089/hum.2006.116. PMID 17328681.