Abruzzese may refer to:
- Neapolitan language, Abruzzese Orientale Adriatico and Abruzzese Occidentale dialects from the Abruzzo region
- Abruzzo region of Italy: Abruzzese is the associated adjective
- The Cane da pastore Maremmano-Abruzzese, sometimes called Cane da pastore Abruzzese or Maremma Sheepdog
- Abruzzese cattle
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