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Acetoxyacetylaminofluorene

From Wikipedia, the free encyclopedia
Acetoxyacetylaminofluorene
Skeletal formula
Ball-and-stick model
Names
Preferred IUPAC name
N-(Acetyloxy)-N-(9H-fluoren-2-yl)acetamide
Other names
N-Acetoxy-N-(9H-fluoren-2-yl)acetamide
N-Acetoxy-2-acetamidofluorene[1]
N-Acetoxy-2-acetylaminofluorene[1]
Acetoxyacetamidofluorene[1]
Acetoxyfluorenylacetamide[1]
Identifiers
3D model (JSmol)
Abbreviations NAAAF
ChEBI
ChEMBL
ChemSpider
MeSH Acetoxyacetylaminofluorene
UNII
  • InChI=1S/C17H15NO3/c1-11(19)18(21-12(2)20)15-7-8-17-14(10-15)9-13-5-3-4-6-16(13)17/h3-8,10H,9H2,1-2H3 checkY
    Key: NFOMHWALMFWNAQ-UHFFFAOYSA-N checkY
  • InChI=1/C17H15NO3/c1-11(19)18(21-12(2)20)15-7-8-17-14(10-15)9-13-5-3-4-6-16(13)17/h3-8,10H,9H2,1-2H3
    Key: NFOMHWALMFWNAQ-UHFFFAOYAD
  • CC(=O)ON(C(C)=O)c1ccc-2c(Cc3ccccc-23)c1
  • CC(=O)ON(C(C)=O)C1=CC=C2C(CC3=C2C=CC=C3)=C1
Properties
C17H15NO3
Molar mass 281.311 g·mol−1
log P 3.327
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Acetoxyacetylaminofluorene is a derivative of 2-acetylaminofluorene used as a biochemical tool in the study of carcinogenesis. It forms adducts with DNA by reacting with guanine at its C-8 position.;[1] This results in breaks in one strand of the DNA.

See also

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References

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  1. ^ a b c d e CID 22469 from PubChem