Adson's sign is the loss of the radial pulse in the arm by rotating head to the ipsilateral side with extended neck following deep inspiration.
Limitations, and pathophysiology of thoracic outlet syndrome
Adson's sign is no longer used as a positive diagnosis of TOS since many people without TOS will show a positive Adson's.
There is minimal evidence of interexaminer reliability.
Thoracic outlet obstruction may be caused by a number of abnormalities, including degenerative or bony disorders, trauma to the cervical spine, fibromuscular bands, vascular abnormalities, and spasm of the anterior scalene muscle. Symptoms are due to compression of the brachial plexus and subclavian vasculature, and consist of complaints ranging from diffuse arm pain to a sensation of arm fatigue, frequently aggravated by carrying anything in the ipsilateral hand or doing overhead work such as window cleaning.
- The patient is placed in a sitting position, hands resting on thighs.
- The examiner palpates radial pulse on side being tested
- Patient actively rotates head to ipsilateral side being tested while the examiner laterally rotates and extends the patient's shoulder
- Patient takes a deep breath and is instructed to hold it
The test is positive if radicular symptoms are reported and secondary to a diminished or lost of the radial pulse. 
- Neurologic Thoracic Outlet Syndrome at eMedicine
- Adson's manoeuvre at Who Named It?
- Malanga GA, Landes P, Nadler SF (April 2003). "Provocative tests in cervical spine examination: historical basis and scientific analyses". Pain physician. 6 (2): 199–205. PMID 16883381.
- Magee, David (2014). Orthopedic Physical Assessment (6th ed.). st. Louis, MI: Elsevier. p. 344. ISBN 978-1-4557-0977-9.