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Both groups of compounds display a range of biological activities, such as cytotoxicity, inhibition of adenosine transfer into rabbit erythrocytes (red blood cells), Ca2+ channel antagonistic action, α1 adrenergic blockade and others.
Both compounds have been reproduced in the laboratory by organic synthesis.
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- Fathi-Afshar, R.; Allen, T. M.; Krueger, C. A.; Cook, D. A.; Clanachan, A. S.; Vriend, R.; Baer, H. P.; Cass, C. E. (April 1989). "Some pharmacological activities of novel adenine-related compounds isolated from a marine sponge". Canadian Journal of Physiology and Pharmacology 67 (4): 276–281. doi:10.1139/y89-045.
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